All-Solid-State Potentiometric Platforms Modified with a Multi-Walled Carbon Nanotubes for Fluoxetine Determination

Abd-Rabboh, Hisham S.M.; Hashem, Heba M.; Shagri, Layla M. S. Al; Amr, Abdel El-Galil E.; Almehizia, Abdulrahman A.; Naglah, Ahmed M.; Kamel, Ayman H.

doi:10.3390/membranes12050446

Cited by 7 publications

(22 citation statements)

References 48 publications

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“…The reference electrode should maintain a stable potential, to avoid drifting during time that can strongly modify the calibration curve of the device. This stability is often achieved by covering the electrode made of a stable and inert metal with a protecting porous membrane that freely enables the exchange of ions, usually made of polyvinyl butyral (PVB) as highlighted in most of the literature [26]- [34].…”

Section: Working Principle Of All-solid-state Ises (Ass-ises)mentioning

confidence: 99%

Ion-Selective All-Solid-State Printed Sensors: A Systematic Review

Polidori,

Tonello,

Serpelloni

2024

IEEE Sensors J.

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The recent advancements in technologies related to printed electronics brought significant innovation in the design and fabrication of electrochemical miniaturized sensors. One of the most exciting categories that can benefit from the transition from macro to micro enabled by novel printing techniques is ion-selective electrodes (ISEs). Miniaturized ISEs are also called All-Solid State ISEs (ASS-ISEs) since they rely on a solid contact transduction layer, enabling easier miniaturization and integration. This is particularly interesting for a wide variety of applications ranging from medical to industrial. In all these fields, printed ASS-ISEs have been proven to reach significant results in terms of metrological properties obtaining near-Nernstian sensitivities, limits of detection down to 10-10, best selectivity coefficients around 10-8, shorter response time lower than 5 s, stability reaching 6 months and optimal variabilities (with best repeatability lower than 1% and reproducibility lower than 2%). The use of innovative printing techniques could further enhance these properties, as well as improve aspects such as flexibility, material waste, resolution improvement, and the finest control of surface functionalization. Even though a wide range of examples has multiplied in the literature over the past decade, to date, most of them still lack uniformity or detailed guidance regarding both the fabrication process and the metrological characterization procedure. With this in mind, this review aims to serve as a guideline for the identification of project specifications for the design, fabrication, and test of ion-selective all-solid-state printed sensors, as well as to propose a common metric in characterizing these devices.

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Section: Working Principle Of All-solid-state Ises (Ass-ises)mentioning

confidence: 99%

Ion-Selective All-Solid-State Printed Sensors: A Systematic Review

Polidori,

Tonello,

Serpelloni

2024

IEEE Sensors J.

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“…The Abd-Rabboh group [ 92 ] showed that screen-printed potentiometric platforms modified with polymers and MWCNTs are capable of detecting trace amounts of fluoxetine, where MWCNTs provide a high potential stability in the sensors compared to the low potential stability in unmodified sensors. They deemed the electrode polarizable, avoiding the ability to buffer any random tiny charge noise [ 92 ].…”

Section: Carbon–polymer Composite-based Modification Of Electrode Sur...mentioning

confidence: 99%

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

et al. 2023

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Selective serotonin re-uptake inhibitors (SSRIs) are one of the most commonly prescribed classes of antidepressants used for the treatment of moderate to severe depressive disorder, personality disorders and various phobias. This class of antidepressants was created with improved margins of safety. However, genetic polymorphism may be responsible for the high variability in patients’ responses to treatment, ranging from failure to delayed therapeutic responses to severe adverse effects of treatment. It is crucial that the appropriate amount of SSRI drugs is administered to ensure the optimum therapeutic efficacy and intervention to minimise severe and toxic effects in patients, which may be the result of accidental and deliberate cases of poisoning. Determining SSRI concentration in human fluids and the environment with high sensitivity, specificity and reproducibility, and at a low cost and real-time monitoring, is imperative. Electrochemical sensors with advanced functional materials have drawn the attention of researchers as a result of these advantages over conventional techniques. This review article aims to present functional materials such as polymers, carbon nanomaterials, metal nanomaterials as well as composites for surface modification of electrodes for sensitive detection and quantification of SSRIs, including fluoxetine, citalopram, paroxetine, fluvoxamine and sertraline. Sensor fabrication, sensor/analyte interactions, design rationale and properties of functional material and the electrocatalytic effect of the modified electrode on SSRI detection are discussed.

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“…For simple and valuable measurement purposes, screen-printed based on ISEs has great attention due to their sensitivity, selectivity, and potential stability 10 . Recently, screen-printed SC- ISEs integrated with polymeric and /or nanomaterials layers have a straightforward approach to monitoring different analytes 18 , 19 .…”

Section: Introductionmentioning

confidence: 99%

A rational study of transduction mechanisms of different materials for all solid contact-ISEs

Hashem,

Abdallah

2024

Sci Rep

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The new era of solid contact ion selective electrodes (SC-ISEs) miniaturized design has received an extensive amount of concern. Because it eliminated the requirement for ongoing internal solution composition optimization and created a two-phase system with stronger detection limitations. Herein, the determination of venlafaxine HCl is based on a comparison study between different ion- to electron transduction materials (such as; multiwalled carbon nanotubes (MWCNTs), polyaniline (PANi), and ferrocene) and illustrating their mechanisms in their applied sensors. Their different electrochemical features (such as bulk resistance (Rb**), double-layer capacitance (Cdl), geometric capacitance (Cg), and specific capacitance (Cp)) were evaluated and discussed by using the Electrochemical Impedance Spectroscopy (EIS), Chronopotentiometry (CP), and Cyclic Voltammetry (CV) experiments. The results indicated that each transducer's influence on the proposed sensor's electrochemical characteristics is determined by their unique chemical and physical properties. The electrochemical features vary for different solid contact materials used in transduction mechanisms. The results confirm that the MWCNT sensor revealed the best electrochemical behavior with the potentiometric response of a near-Nernestian slope of 56.1 ± 0.8 mV/decade with detection limits of 3.8 × 10−6 mol/L (r2 = 0.999) and a low potential drift (∆E/∆t) of 34.6 µV/s. Also, the selectivity study was performed in the presence of different interfering species either in single or complex matrices. This demonstrates excellent selectivity, stability, conductivity, and reliability as a VEN-TPB ion pair sensor for accurately measuring VEN in its various formulations. The proposed method was compared to HPLC reported technique and confirmed no significant difference between them. So, the proposed sensors fulfill their solutions' demand features for VEN appraisal.

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All-Solid-State Potentiometric Platforms Modified with a Multi-Walled Carbon Nanotubes for Fluoxetine Determination

Cited by 7 publications

References 48 publications

Ion-Selective All-Solid-State Printed Sensors: A Systematic Review

Ion-Selective All-Solid-State Printed Sensors: A Systematic Review

Review on Surface-Modified Electrodes for the Enhanced Electrochemical Detection of Selective Serotonin Reuptake Inhibitors (SSRIs)

A rational study of transduction mechanisms of different materials for all solid contact-ISEs

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