Allele frequencies of 15 autosomal STR loci in the southern Morocco population with phylogenetic structure among worldwide populations

Ossmani, Hicham El; Talbi, Jalal; Bouchrif, Brahim; Chafik, Abdelaziz

doi:10.1016/j.legalmed.2009.01.053

Cited by 20 publications

(9 citation statements)

References 15 publications

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“…D21S11 and D18S51 loci illustrate the largest number of different alleles. The following locations, the most common alleles at the 21 loci, were allele 13 for (D5S818, D8S1179 and D18S51), allele 10 for (D7S820 and Penta D), allele 16 for ( makes them the markers of favorite in properties and genetic diversity studies (Ossmani et al, 2009;Chouery et al, 2010;Imad et al, 2014d). The best indicator of the genetic polymorphism within the sample is verified by the number of alleles and the expected heterozygosity found in the Iraq population.…”

Section: Allele Frequency Of Common Autosomal Genetic Locimentioning

confidence: 93%

Detection of new variant Off-ladder at the D12S391, D19S433 and D1S1656 loci and tri-allelic pattern at the D16S539 locus in a 21 locus autosomal short tandem repeat database of 400 Iraqi Individuals

Jebor¹,

Hameed²,

Kareem³

2015

Afr. J. Biotechnol.

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The objectives of the study included the detection of genetic variation of 21 autosomal short tandem repeats (STRs) loci from random unrelated individuals in the middle and South Arab people of Iraq, the Forensic efficiency parameters of the autosomal 21 genetic loci using power plex21® kit and to evaluate the importance of these loci for forensic genetic purposes and the possibility to use the new kit in routine practical work. FTA® Technology was utilized to extract DNA from blood collected on FTA™ paper. Twenty one (21) STR loci including D3S1358, D13S317, D19S433 and Amelogenin were amplified by using power plex21® kit. PCR products were detected by genetic analyzer 3130xL then, the data processed and analyzed by PowerStatsV1.2 software. Several statistical parameters of genetic and forensic efficiencies based on allelic frequencies have been estimated. This includes the observed heterozygosity (Ho), expected heterozygosity (He), paternity index (PI), random match probability (RMP), power of discrimination (PD), chance of exclusion (CE), polymorphic information content (PIC) and P-value. The power of discrimination values for autosomal tested loci was from 75 to 96% therefore those loci can be safely used to establish a DNA-based database for Iraq population for identifical purpose. The high PIC values of the selected markers confirm their usefulness for genetic polymorphism studies and linkage mapping programs in human as well. The mean heterozygosity observed, expected and mean PIC values across the 20 loci were 0.79, 0.83 and 0.81, respectively indicating high gene diversity. A total of nine off-ladder alleles and one tri-allelic pattern were detected in this study.

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Section: Allele Frequency Of Common Autosomal Genetic Locimentioning

confidence: 93%

Detection of new variant Off-ladder at the D12S391, D19S433 and D1S1656 loci and tri-allelic pattern at the D16S539 locus in a 21 locus autosomal short tandem repeat database of 400 Iraqi Individuals

Jebor¹,

Hameed²,

Kareem³

2015

Afr. J. Biotechnol.

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“…Tests for Hardy–Weinberg equilibrium were performed in Arlequin v3.5.1.319. Since the statistical analyses in this study were on the basis of Bayesian-clustering algorithm, raw genotypic data of 13 STRs (excluding D6S1043 and D12S391) from 59 populations all around the world were extracted to determine population affinity1420212223242526272829303132333435363738394041424344454647484950. Analysis of molecular variance (AMOVA), average number of pairwise differences, pairwise Fst, Slatkins linearized Fst, and coancestry coefficients were all calculated in Arlequin v3.5.1.319 using genotype data.…”

Section: Methodsmentioning

confidence: 99%

Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci

Yao

Wang

et al. 2017

Sci Rep

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The origin and diversification of Sino-Tibetan speaking populations have been long-standing hot debates. However, the limited genetic information of Tibetan populations keeps this topic far from clear. In the present study, we genotyped 15 forensic autosomal short tandem repeats (STRs) from 803 unrelated Tibetan individuals from Gansu Province (635 from Gannan and 168 from Tianzhu) in northwest China. We combined these data with published dataset to infer a detailed population affinities and genetic substructure of Sino-Tibetan populations. Our results revealed Tibetan populations in Gannan and Tianzhu are genetically very similar with Tibetans from other regions. The Tibetans in Tianzhu have received more genetic influence from surrounding lowland populations. The genetic structure of Sino-Tibetan populations was strongly correlated with linguistic affiliations. Although the among-population variances are relatively small, the genetic components for Tibetan, Lolo-Burmese, and Han Chinese were quite distinctive, especially for the Deng, Nu, and Derung of Lolo-Burmese. Han Chinese but not Tibetans are suggested to share substantial genetic component with southern natives, such as Tai-Kadai and Hmong-Mien speaking populations, and with other lowland East Asian populations, which implies there might be extensive gene flow between those lowland groups and Han Chinese after Han Chinese were separated from Tibetans. The dataset generated in present study is also valuable for forensic identification and paternity tests in China.

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“…Tests for Hardy–Weinberg equilibrium (HWE) were performed in Arlequin v3.5.1.312 using a likelihood ratio test and an exact test to prevent miscalling STR genotypes or biased sampling. Since the statistical analyses in this study were on the basis of Bayesian-clustering algorithm, raw genotypic data of 13 STRs (excluding D6S1043 and D12S391) from 45 populations (13793 individuals) all around the world were extracted to determine population affinity131415161718192021222324252627282930313233343536373839. Average number of pairwise differences, pairwise Fst, Slatkins linearized Fst, and coancestry coefficients were all calculated in Arlequin v3.5.1.3 using genotype data12.…”

Section: Methodsmentioning

confidence: 99%

Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui

Yao

Wang

Tao

et al. 2016

Sci Rep

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There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry. Our analysis found no evidence of substantial gene flow from Middle East or Europe into Dongxiang and Hui people during their Islamization. The dataset generated in present study are also valuable for forensic identification and paternity tests in China.

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Allele frequencies of 15 autosomal STR loci in the southern Morocco population with phylogenetic structure among worldwide populations

Cited by 20 publications

References 15 publications

Detection of new variant Off-ladder at the D12S391, D19S433 and D1S1656 loci and tri-allelic pattern at the D16S539 locus in a 21 locus autosomal short tandem repeat database of 400 Iraqi Individuals

Detection of new variant Off-ladder at the D12S391, D19S433 and D1S1656 loci and tri-allelic pattern at the D16S539 locus in a 21 locus autosomal short tandem repeat database of 400 Iraqi Individuals

Genetic structure of Tibetan populations in Gansu revealed by forensic STR loci

Genetic evidence for an East Asian origin of Chinese Muslim populations Dongxiang and Hui

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