Allele frequencies of 15 autosomal STR loci in the Caymanian population

Faris, Jonathan S.; Tanzillo-Swarts, Angela

doi:10.1007/s00414-014-1090-1

Cited by 2 publications

(2 citation statements)

References 8 publications

(10 reference statements)

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“…In accordance with the previous reports of STR locus frequency, pairwise GD (genetic distance) values between the Chinese group and 8 neighboring groups (Romanian, Estonian, Iranian, Cayman Islander, South African, Brazilian, Libyan and Korean) were calculated and the data is shown in Supp. Table S2 ( Lee et al, 2010 , Aguiar et al, 2012 , Khodjet-el-Khil et al, 2012 , Hedjazi et al, 2013 , Anghel et al, 2014 , Lucassen et al, 2014 , Sadam et al, 2014 , Faris and Tanzillo-Swarts, 2015 ). Phylogenetic reconstruction was conducted to illustrate the genetic relationships and the UPGMA tree is shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

Zhao¹,

Zhang

Wang³

et al. 2015

Meta Gene

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STR, short tandem repeats, are well known as a type of powerful genetic marker and widely used in studying human population genetics. Compared with the conventional genetic markers, the mutation rate of STR is higher. Additionally, the mutations of STR loci do not lead to genetic inconsistencies between the genotypes of parents and children; therefore, the analysis of STR mutation is more suited to assess the population mutation. In this study, we focused on 15 autosomal STR loci. DNA samples from a total of 42,416 unrelated healthy individuals (19,037 trios) from the population of Mainland China collected between Jan 2012 and May 2014 were successfully investigated. In our study, the allele frequencies, paternal mutation rates, maternal mutation rates and average mutation rates were detected. Furthermore, we also investigated the relationship between paternal ages, maternal ages, area, the time of pregnancy and average mutation rate. We found that the paternal mutation rate was higher than the maternal mutation rate and the paternal, maternal, and average mutation rates had a positive correlation with paternal age, maternal age and the time of pregnancy respectively. Additionally, the average mutation rate of coastal areas was higher than that of inland areas.

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Section: Resultsmentioning

confidence: 99%

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

Zhao¹,

Zhang

Wang³

et al. 2015

Meta Gene

View full text Add to dashboard Cite

show abstract

“…And we could observe that the CPE of 30 Indel loci in various populations changed within a narrow scope. Collectively, the CPE values using the kit were relatively lower and could not reach a high level of exclusion in forensic paternity cases compared to STR genetic markers [29, 30]. Nonetheless, the CDP values had the ability to provide considerable level of discrimination when the kit came to forensic identification cases.…”

Section: Discussionmentioning

confidence: 99%

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations

et al. 2017

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Thirty insertion/deletion loci were utilized to study the genetic diversities of 125 bloodstain samples collected from Bai group in Yunnan Dali region, China. The observed heterozygosity and expected heterozygosity of the 30 loci ranged from 0.1520 to 0.5680, and 0.1927 to 0.4997, respectively. No deviations from Hardy-Weinberg equilibrium tests after Bonferroni correction were found at all 30 loci in Bai group. The cumulative probability of exclusion and combined discrimination power were 0.9859 and 0.9999999999887, respectively, which indicated the 30 loci could be used as complementary genetic markers for paternity testing and were qualified for personal identification in forensic cases. We found the studied Bai group had close relationships with Tibetan, Yi and Han groups from China by the population structure, principal component analysis, population differentiations, and phylogenetic reconstruction studies. Even so, for a better understanding of Bai ethnicity's genetic milieu, DNA genotyping at various genetic markers is necessary in future studies.

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Allele frequencies of 15 autosomal STR loci in the Caymanian population

Cited by 2 publications

References 8 publications

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

Mutation rate estimation for 15 autosomal STR loci in a large population from Mainland China

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations

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