Allele frequency distribution for 15 autosomal STR loci in Afridi Pathan population of Uttar Pradesh, India

Noor, Sabahat; Ali, Shahnaz; Eaaswarkhanth, Muthukrishnan; Haque, Ikramul

doi:10.1016/j.legalmed.2009.08.002

Cited by 9 publications

(10 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, D7S820 was the only marker showing very small differences among the population studied, whereas, the marker with highest contribution to interpopulation genetic differences was vWA. Furthermore, not many studies have been done in these population groups to compare the present results (Reddy et al 2005;Khan et al 2007;Noor et al 2009). The results suggested that the present marker system actually meets all the existing requirements and can be used for DNA typing and population studies.…”

Section: Discussionmentioning

confidence: 86%

Analysis of TNFRSF1A Gene R92Q Mutation in Familial Mediterranean Fever

Yuce

Bağcı

2014

IJHG

View full text Add to dashboard Cite

Historically, Punjab has served a major passage way for human migration to Indian subcontinent and has influenced the genetic structure of extant populations in Punjab. Therefore, Punjabi population possesses an exclusive genetic profile primarily due to the many migratory events in this region which caused an extensive range of genetic diversity. Hence, the present study is an attempt to understand the effect of these influences on genetic differentiation, diversity a nd popula tion structure of Punjab. Genetic polymorphism at five highly polymorphic short tandem repeat loci (STR) is studied in four endogamous population groups of Punjab, India. The studied groups included Jat Sikh, Majbi Sikh, Brahmin and Ramdasia to evaluate their significance in human identification and genetic study. All selected groups practice endogamy and a total of 358 individuals belonging to these four endogamous groups were studied for five highly polymorphic with greater power of exclusion STR loci: THO1, TPOX, D7S820, CSF1PO and vWA. The highest observed heterozygosity was found in Ramdasia population for almost all the markers except vWA which had highest observed heterozygosity among Majbi Sikh population group. In this study, the average sub-ethnic differentiation (Fst) among the four populations of north-west Punjab was 0.0821. The marker with the highest contribution to interpopulation genetic difference was obser ved to be vWA.

show abstract

Section: Discussionmentioning

confidence: 86%

Analysis of TNFRSF1A Gene R92Q Mutation in Familial Mediterranean Fever

Yuce

Bağcı

2014

IJHG

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 90%

“…Additional work by Narasimhan et al (2019) confirmed that early Iranian agriculturalists from the Zagros Mountains harbor a distinctive type of West Eurasian ancestry (see also Broushaki et al, 2016; Lazaridis et al, 2016), but these researchers also found that later groups found to the east show evidence of contributions from both Anatolian and Zagros Mountain agriculturalists. In fact, the archeologically documented spread of a shared package of plants (Miller, 1999) and animal domesticates coincides with the extent of Anatolian farmer‐related contribution leading to a west‐to‐east cline Narasimhan et al (2019) designate as the “Southwest Asian Cline.” The Anatolian farmer‐related contribution ranged from a high of ~70% in Chalcolithic Anatolia, to ~31% in eastern Iran, to ~7% in far eastern Turan (Turkmenistan, Uzbekistan, Iranian Khorassan) and is accompanied by a concomitant increase in the early Iranian farmer‐related contribution. Further, these researchers found that by the 3rd millennium BC populations residing within the far eastern part of this cline are marked by gene flow from West Siberian hunter‐gatherers ( WSHG ), which suggests that North Eurasian admixture impacted populations residing in Turin prior to the spread of Yamnaya‐related steppe pastoralists ( Steppe_EMBA ) whose ancestral profile attests to a greater contribution from Eastern European Hunter Gatherer ( EEHG ) than WSHG ancestry.…”

Section: Introductionmentioning

confidence: 90%

“…In recent years a reformulated version of the HCCM has received considerable support from molecular genetic studies (Barnabas et al, 1996; Basu et al, 2003; Cordaux et al, 2004; de Barros Damgaard et al, 2018; Moorjani et al, 2013; Narasimhan et al, 2019; Passarino et al, 1996; Quintana‐Murci et al, 2001; Wells et al, 2001). In its reconfiguration proponents of the HCCM no longer call for the destruction of the Harppan cities at the hands of invading Central Asians, nor do they call for replacement of the resident population by an exogenous population from Central Asia.…”

Section: Introductionmentioning

confidence: 99%

“…Proponents of the reconfigured HCCM call for the introduction of Central Asian ancestry into the Indus Valley and admixing with members of the local population. Two different versions of this model are offered by de Barros Damgaard et al (2018) and Narasimhan et al (2019). According to de Barros Damgaard et al, apart from Austro‐Asiatic and Tibeto‐Burman populations, post‐Harappan affinities among South Asians may ultimately be traced to two sources, Chalcolithic era farmers of the Namazga polity that preceded the BMAC of Central Asia and indigenous South Asians whose affinities may ultimately be traced to the diaspora of modern humans out of Africa.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The role of Hazarewal populations in the peopling of South Asia: A dental morphology investigation

Akbar

Ullah

Ahmad

et al. 2023

American Journal of Biological Anthropology

View full text Add to dashboard Cite

Objectives: This study seeks to accomplish three objectives: assess the biological impact of historically documented Pathan-speaking populations on present-day Hazarewal ethnic groups, determine consilience in patterns of relationships identified by molecular genetics and dental morphology analyses, and determine which of the current models for the peopling of the Indian subcontinent is best supported by dental morphology analysis. Materials and Methods: Dental morphology traits were scored with the Arizona State University Dental Anthropology System among living members of 18 ethnic group samples from South Asia in northern Pakistan and 13 prehistoric samples from south-central Asia and South Asia. Affinities were summarized with raw percentages and Smith's MMD. Affinities based on the former were accomplished with correspondence analysis and principal components analysis. Affinities based on the latter were undertaken with neighbor-joining cluster analysis and multidimensional scaling. Results: Biodistances based on 17 tooth-trait combinations suggest the human biological history in South Asia is dominated by long-standing continuity, but this continuity is not absolute. There is no evidence for influx of Central Asians or Pathan influences on Hazarewal ethnic groups. Instead, gene flow likely occurred, albeit from other sources, near the beginning of the Holocene and at the beginning of the Iron Age. Discussion: Consilience in results obtained with molecular genetics and dental morphology analyses is good. Both indicate long-standing population continuity over time and clinal variation emanating from Hazarewal to the south and east. However, dental morphology suggests an early Holocene influx of exogenous genes, perhaps from southern Iran, while ruling out a steppe-based influx during the mid-2nd millennium BC.

show abstract

Genetic analysis of 15 autosomal STRs in Yousafzai population of Pakistan

et al. 2018

View full text Add to dashboard Cite

Yousafzai is a Pushto-speaking Pathan tribe inhabiting the northern province of Pakistan who claim to be descendants of the prophet Yousaf (Joseph). Forensic and genetic parameters were determined for 203 genetically unrelated individuals on 15 autosomal STRs. D2S1338 was the most discriminating locus whereas TPOX was the least. The combined matching probability (CMP) for all loci was 1.52458 × 10 while combined power of discrimination (CPD) and combined power of exclusion (CPE) was 0.9999999999999999984 and 0.999998628, respectively. The Yousafzai population was in Hardy-Weinberg equilibrium after Bonferroni correction except for loci D3S1358 and D19S433. Pairwise genetic distance analysis was carried out by comparing with various populations at local and global levels. The findings of this study are valuable for population genetics and forensics analysis.

show abstract

Allele frequency distribution for 15 autosomal STR loci in Afridi Pathan population of Uttar Pradesh, India

Cited by 9 publications

References 10 publications

Analysis of TNFRSF1A Gene R92Q Mutation in Familial Mediterranean Fever

Analysis of TNFRSF1A Gene R92Q Mutation in Familial Mediterranean Fever

The role of Hazarewal populations in the peopling of South Asia: A dental morphology investigation

Genetic analysis of 15 autosomal STRs in Yousafzai population of Pakistan

Contact Info

Product

Resources

About