Allergic bronchopulmonar aspergillosis in asthmatic patients

Kozlova, Y I; Козлова, Я И; Соболев, А В; Фролова, Е. В.; Аак, О В; В, Аак О; Burygina, E V; Климко, Н Н; Климко, Н Н

doi:10.36691/rja455

Cited by 2 publications

(2 citation statements)

References 48 publications

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Section: Microorganisms Concentrations and Diversitymentioning

confidence: 97%

“…According to the results of studies conducted in pulmonology clinics in different countries, the frequency of sensitization to Aspergillus spp. in patients with bronchial asthma in China was 5.5%; in New Zealand 18.4%; in Saudi Arabia 22.6%; in India 38.5%; in Russia 36%; the number of patients with this disease in the world is approximately 6 million, in Russia this number is 175 thousand [44][45][46]. Gram-positive endospore-forming bacteria of the genera Lysinibacillus and Bacillus were most abundant in aerosols at altitudes of 200-300 m, accounting for up to 97.8% of the total number of microbial isolates isolated from the sample (Figure 2).…”

Section: Microorganisms Concentrations and Diversitymentioning

confidence: 99%

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Culturable Microorganisms of Aerosols Sampled during Aircraft Sounding of the Atmosphere over the Russian Arctic Seas

Andreeva,

Safatov,

Puchkova

et al. 2024

Atmosphere

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Atmospheric sounding using the Tu-134 Optik aircraft-laboratory was conducted in September 2020 over the seas of the Russian sector of the Arctic Ocean, namely the Barents, Kara, Laptev, East Siberian, Chukchi and Bering seas. Unique samples of atmospheric aerosols at altitudes from 200 and up to 10,000 m were taken, including samples for the identification of cultivated microorganisms and their genetic analysis. Data on the concentration and diversity of bacteria and fungi isolated from 24 samples of atmospheric aerosols are presented; the main phenotypic and genomic characteristics were obtained for 152 bacterial cultures; and taxonomic belonging was determined. The concentration of cultured microorganisms detected in aerosols of different locations was similar, averaging 5.5 × 103 CFU/m3. No dependence of the number of isolated microorganisms on the height and location of aerosol sampling was observed. The presence of pathogenic and condto shitionally pathogenic bacteria, including those referred to in the genera Staphylococcus, Kocuria, Rothia, Comamonas, Brevundimonas, Acinetobacter, and others, as well as fungi represented by the widely spread genera Aureobasidium, Aspergillus, Alternaria, Penicillium, capable of causing infectious and allergic diseases were present in most analyzed samples. Obtained data reveal the necessity of systematic studies of atmospheric microbiota composition to combat emerging population diseases.

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Section: Microorganisms Concentrations and Diversitymentioning

confidence: 97%

Section: Microorganisms Concentrations and Diversitymentioning

confidence: 99%

Culturable Microorganisms of Aerosols Sampled during Aircraft Sounding of the Atmosphere over the Russian Arctic Seas

Andreeva,

Safatov,

Puchkova

et al. 2024

Atmosphere

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Possibilities of CT in the diagnosis of pulmonary aspergillosis in patients with COVID-19 (literature review)

Nay,

Yudin,

Abovich

2023

Medicinskaâ vizualizaciâ

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Aim: to analyze the latest research in the field of CT diagnostics of pulmonary aspergillosis in patients with COVID-19 according to domestic and foreign literature.Results. Pulmonary aspergillosis is one of the most common life-threatening fungal diseases that is caused by inhalation of Aspergillus mold spores and affects all parts of the respiratory system. In recent years, there has been a sharp increase in cases of invasive mycotic processes. During the COVID-19 pandemic, according to a number of authors, the incidence of pulmonary aspergillosis reached 34.4%, and the mortality rate was 74%. The World Health Organization calls for “minimizing the disproportionate use of corticosteroids and antibiotics for mild and moderate cases”. She explained that corticosteroids in severe cases do save lives, but their massive use can cause fungal infections. This complication is increasingly common in patients after corticosteroid and antibiotic therapy, with immunodeficiency states, as well as those treated in intensive care units. The COVID-19 pandemic has created additional challenges in the diagnosis, treatment and prevention of fungal complications. The clinical and radiographic features of fungal infections are largely similar to typical pulmonary manifestations of COVID-19. A comparative analysis of CT signs of various forms of pulmonary aspergillosis before and during the COVID-19 pandemic was carried out according to the literature. The main CT symptoms of mycotic lung lesions among patients who have undergone COVID-19 have been identified. Currently, computed tomography is crucial, first of all, to detect and monitor complications of COVID-19, including the addition of a secondary fungal infection.Conclusion. To make a conclusion about mycosis in the early stages, special vigilance and high qualification of the radiologist are required, which in turn will contribute to the timely appointment of antifungal therapy, which will reduce morbidity and mortality.

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Allergic bronchopulmonar aspergillosis in asthmatic patients

Cited by 2 publications

References 48 publications

Culturable Microorganisms of Aerosols Sampled during Aircraft Sounding of the Atmosphere over the Russian Arctic Seas

Culturable Microorganisms of Aerosols Sampled during Aircraft Sounding of the Atmosphere over the Russian Arctic Seas

Possibilities of CT in the diagnosis of pulmonary aspergillosis in patients with COVID-19 (literature review)

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