Allergic conjunctivitis in Asia

Thong, Bernard Yu‐Hor

doi:10.5415/apallergy.2017.7.2.57

Cited by 34 publications

(29 citation statements)

References 51 publications

(50 reference statements)

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“…Allergens and allergic mediators drain to the nose by this pathway, generating nasal symptoms. The conjunctiva and the nose make up an entire system [1,2,[5][6][7][8]. This can also be explained, allergic rhinitis and conjunctivitis were always co-existent and persistent to repeatedly happen.…”

Section: Discussionmentioning

confidence: 99%

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A survey of seasonal and perennial allergic conjunctivitis in children in southwest China: a case-control study

Qin

Hong

gao

2020

Preprint

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Background Seasonal allergic conjunctivitis (SAC) and perennial allergic conjunctivitis (PAC) were the most usual types of allergic conjunctivitis. House dust mites were the most common sensitization agents for SAC and PAC. This study aimed to explore SAC and PAC risk factors in children. Methods We recruited 176 children suffering from SAC or PAC and 131 control subjects in southwest China. A questionnaire , several eye exams and the skin prick test (SPT) were performed.The scores of the symptoms/signs were recorded. Results The percentage of children that had ever been breastfed in the case group was lower than in the control group (P<0.05). The rate of parental allergy history in the case group was higher than for the control group (P<0.01). Compared with the control group, the case group was more likely to have other systemic allergic diseases (P<0.01).The incidence rate of adenoidal hypertrophy (ATH) in case group was higher than control group (P<0.05). The ocular symptoms and signs scores had signi cant correlation to the course (P<0.05), but no correlation to the SPT results (P>0.05). Conclusion Allergic conjunctivitis may coexist with a variety of allergic diseases, and SAC and PAC may be a risk factor for ATH. Breastfeeding should be recommended, as it may be an alleviating factor for allergic diseases, especially for children of parents with a history of allergic diseases. The disease severity is closely related to its course. Therefore, to avoid di culty in treatment caused by the aggravation of symptoms and signs, timely antiallergic treatment was recommended.

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Section: Discussionmentioning

confidence: 99%

“…SAC and PAC are mediated by type I (IgEmediated hypersensitivity) reactions [4]. PAC is considered to be a variant of SAC that persists throughout the year; 79% of patients who have PAC experience a seasonal exacerbation [5].Although the symptoms of SAC and PAC are mild, they affect the quality of life [6].…”

Section: Introductionmentioning

confidence: 99%

A survey of seasonal and perennial allergic conjunctivitis in children in southwest China: a case-control study

Qin

Hong

gao

2020

Preprint

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“…In southwest China, air pollution is more serious than in developed country. Outdoor air pollution is a major risk factor for conjunctivitis, and the key contributors are fuel combustion and dust storms [29]. In addition, the climate is humid in southwest China, which provides favorable conditions for the growth of dust mites.…”

Section: Discussionmentioning

confidence: 99%

Association between allergic conjunctivitis and provisional tic disorder in children

Chen

Ning

et al. 2019

Int Ophthalmol

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Background Allergic diseases are associated with a higher risk of Tourette's syndrome (TS). Provisional tic disorder (PTD) and eye blinking are often reported as the initial symptoms both in TS and in allergic conjunctivitis (AC). Objective To investigate the association between AC and PTD in children of 4-10 years of age in southwest China. Methods This case-control study was carried out at the Children's Hospital of Chongqing Medical University between January 2016 and June 2017. Age-and gender-matched children without PTD were included as the control group. Intraocular pressure was measured by non-contact tonometry, tear film breakup time by slit-lamp examination, and allergens by skin prick test (SPT). Multivariable logistic regression analysis was applied to adjust for the simultaneous effects of AC, dry eye, and allergic history in children with PTD. Results The frequency of AC was higher in the PTD group (74.3%, 52/70) than in the control group (17.1%, 12/70) (P \ 0.001). The frequencies of positive SPT were found to be higher in the PTD group (80.0%, 56/70) than in the control group (20.0%, 14/70). AC, dry eye, and history of allergic rhinitis were significantly associated with PTD. Conclusion The frequencies of AC are high in children with PTD. AC and dry eye may be both associated with PTD in children.

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“…Continuous uncontrolled inflammation can result in permanently reduced or a complete loss of vision in children suffering from VKC. Topical corticosteroids are among the most potent pharmacologic agents used to treat the more severe variants of ocular allergies, as well as acute and chronic forms of AC [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study

et al. 2017

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Among the anti-inflammatory medications used for treating asthma, corticosteroids are the most effective. The effects of orally administered corticosteroids on intraocular pressure and lens opacity have been well defined, but the influence of inhaled corticosteroids (ICS) on children has yet to be clearly explained. Therefore, we used a nationwide cohort database to investigate glaucoma in childhood asthma patients using ICS. We analyzed a dataset of 1,000,000 randomly sampled individuals from Taiwan's 2000 National Health Insurance Research Database. The study cohort included 5,380 patients who were first diagnosed with asthma (ICD9: 493.X) diagnosis when they were six years old or younger. All subjects were followed through December 2011. We applied Cox's proportional hazard model to determine whether ICS use has a correlation with glaucoma. Of the 5,380 patients enrolled in this study, we identified 1,232 patients who had used ICS and 4,148 patients who had no history of ICS administration throughout the follow-up period. The prevalence of glaucoma was significantly lower in patients using ICS, with a 0.52-fold decreased risk of developing glaucoma in comparison to the control group [adjusted hazard ratio (HR) 0.52, 95% confidence interval (CI) 0.28∼0.96]. Among the evaluated comorbidities, cataract was positively associated with glaucoma in asthma children (adjusted HR 8.22; 95% CI = 2.59∼26.12). This study provides not only the first but also strong evidence that the glaucoma incidence in the ICS group is lower than that in the non-ICS group in children with asthma. Further consultation with an ophthalmologist regarding the high-risk group of asthma children with cataracts is necessary.

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Allergic conjunctivitis in Asia

Cited by 34 publications

References 51 publications

A survey of seasonal and perennial allergic conjunctivitis in children in southwest China: a case-control study

A survey of seasonal and perennial allergic conjunctivitis in children in southwest China: a case-control study

Association between allergic conjunctivitis and provisional tic disorder in children

Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study

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