Allergic contact dermatitis caused by poly(adipic acid‐co‐1,2‐propylene glycol) and di‐(n‐octyl) tin‐bis(2‐ethylhexylmaleate) in vinyl chloride gloves

Triphenyl phosphite, a new allergen in polyvinylchloride gloves

“…Patch test reactions to PVC gloves seem to be relatively common among our patients. The evidence for allergens in PVC is increasing (2–12, 17, 20). In our experience, raw materials or detailed information on the ingredients are difficult to obtain from glove manufacturers.…”

“…Despite their extensive use, contact allergy to PVC gloves has been reported relatively seldom, and, in many cases, the specific allergens have remained unknown. The allergens identified so far in PVC gloves include organic pigments (2, 3), bisphenol A (4, 5), adipic polyester (6), formaldehyde (7), benzisothiazolinone (8, 9), di‐(n‐octyl)‐tin‐bis(2‐ethylhexylmaleate) and/or polyadipic acid propylene glycol (10), and 2‐ethylhexylmaleate (11). Some studies have indicated that contact allergy to PVC gloves might be as common as that to rubber gloves, and problems in obtaining detailed information on the ingredients of PVC gloves may complicate the diagnosis of PVC glove‐allergic patients (12).…”

Tricresyl phosphate in polyvinylchloride gloves: a new allergen

“…reported five cases of allergic contact dermatitis caused by TPPi in PVC medical gloves . The other allergens incriminated are biocides, plasticizers, stabilizers, and pigments: benzisothiazolinone , formaldehyde , mono(2‐ethylhexyl) maleate , di‐(n‐octyl)‐tin‐bis(2‐ethylhexylmaleate) and polyadipic acid‐co1,2 propylene glycol , pigments and dyes, a reddish‐copper phthalocyanine‐blue complex , an organic pigment, Irgalite Orange F2G , bisphenol A ( ), and adipic polyester .…”

“…In spite of their widespread use, only a few cases of allergic contact dermatitis caused by PVC gloves (6), di-(n-octyl)-tin-bis(2ethylhexylmaleate) and polyadipic acid-co1,2 propylene glycol (7), pigments and dyes, a reddish-copper phthalocyanine-blue complex (8), an organic pigment, Irgalite Orange F2G (9), bisphenol A (10, 11), and adipic polyester (12). TCP (CAS no.…”

A review of the materials and allergens in protective gloves

“…These compounds are added to plastics in small amounts (<5%) to harden them or in large amounts (30–50%) to soften them. There have been isolated reports of the plasticizers, adipic polyester (level of evidence A) and poly(adipic acid‐ co ‐1,2‐propylene glycol) causing allergic contact dermatitis (32,33). In the latter case, this was also associated with positive patch testing to the stabilizer di‐(n‐octyl) tin‐bis(2‐ethylhexylmaleate) (level of evidence A), which has also been reported as the responsible allergen in isolation (level of evidence A) (34).…”