Allergic contact dermatitis from acrylates in insulin pump infusion sets

Sensitization to cyanoacrylates caused by prolonged exposure to a glucose sensor set in a diabetic child

“…To our knowledge, no other case of contact allergy to a cyanoacrylate resulting from such an exposure has previously been published. The increased use of medical devices, beneficial as they are for disease control, may have a negative impact on the quality of life of the patient, as described in this specific case and in others (1)(2)(3)(4)8). Patients wearing medical devices on their skin who subsequently experience eczema should be thoroughly patch tested.…”

“…Monitoring of blood glucose and administration of insulin are pivotal in the treatment of type 1 diabetes mellitus in children. Adverse effects such as skin problems caused by glucose sensor sets or insulin pumps are rarely reported (1)(2)(3)(4). We present a child with newly diagnosed type 1 diabetes mellitus who developed allergic contact dermatitis caused by contact allergy to a cyanoacrylate used in the glue for the fabric parts of a glucose sensor set.…”

Allergic contact dermatitis caused by isobornyl acrylate in OmniPod, an innovative tubeless insulin pump

“…5 One case report described a patient who reacted to several (meth)acrylates, but the authors could not obtain samples of the glue components to complete the work-up, as is unfortunately often the case. 6 In 1995, contact allergy to IBOA was reported in 2 young women who developed eczema and abscesses around the injection sites of their insulin pumps. 3 They showed contact-allergic reactions to components of the adhesive glue and to plastic scrapings from the infusion set.…”

Allergic contact dermatitis caused by medical devices for diabetes patients: A review

“…6 In 2001, the presence of PEEA in the infusion set 7 was confirmed by means of gas chromatographic analysis, 7 with similar ACD cases being described later. 8 The different allergens detected by patch testing are shown in Table 1. which is considered to be the main allergen in this setting.…”