Allergic contact dermatitis from phthalic anhydride/trimellitic anhydride/glycols copolymer in nail varnish

Moffitt, D. L.; Sansom, Jane

doi:10.1034/j.1600-0536.2002.460409.x

Cited by 30 publications

(16 citation statements)

References 6 publications

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“…As a result of the numerous cases of TSFR sensitivity, the cosmetic industry has responded by producing “TSFR‐free” nail enamel with various copolymers and resins. Unfortunately, cases of ACD have been reported with these compounds as well, most notably with the copolymer phtalic anhydride/trimellitic anhydride/glycols and methyl acrylate (20–23).…”

Section: Introductionmentioning

confidence: 99%

Contact and primary irritant dermatitis of the nail unit diagnosis and treatment

Militello

2007

Dermatol Ther

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Contact dermatitis of the nail unit is not rare. The most common allergens are found in nail cosmetics such as enamel, sculptured nails, and preformed plastic tips. Toluene sulfonamide formaldehyde resin, acrylates, and ethylcyanoacrylate are the most common allergens. Along with a proper clinical history focusing on nail practices, a thorough understanding of the common allergens and patch testing are necessary to diagnose contact dermatitis. A discussion of the common allergens and irritants relevant to the nail unit will be presented.

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Section: Introductionmentioning

confidence: 99%

Contact and primary irritant dermatitis of the nail unit diagnosis and treatment

Militello

2007

Dermatol Ther

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“…Trimellitic anhydrides are also used in the production of adhesives, polymers, dyes, and printing inks. Phthalic anhydride was introduced a few years ago in some formulations of nail polishes as an alternative to toluenesulfonamide formaldehyde resin (17, 18).…”

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confidence: 99%

“…Allergic contact dermatitis to PTG copolymer Phthalic and trimellitic anhydrides have both been well documented as causing respiratory irritancy and allergy mediated via specific immunoglobulin E antibodies. Allergic contact urticaria and contact dermatitis have been described following airborne exposure in factory workers (18). Contact allergy to PTG copolymer in nail varnish was first reported by Moffitt and Sansom (18) in 2002.…”

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confidence: 99%

“…Allergic contact urticaria and contact dermatitis have been described following airborne exposure in factory workers (18). Contact allergy to PTG copolymer in nail varnish was first reported by Moffitt and Sansom (18) in 2002. In 2004, le Coz et al presented 3 further cases of allergic contact dermatitis to PTG copolymer in nail varnish (16), while Gach et al (17) reported the largest series of cases (4) in 2005.…”

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confidence: 99%

“…These reactions are commonly caused by allergy to tosylamide/formaldehyde resin. Other reported allergens in nail varnish include formaldehyde, nitrocellulose, guanine, polyester resin, acrylates, acetates, and pigments (18, 19). In the case of PTG copolymer allergic contact dermatitis, the use of tosylamide/formaldehyde‐based nail polish is an alternative (16).…”

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Allergic contact dermatitis to copolymers in cosmetics – case report and review of the literature

et al. 2006

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Copolymers or heteropolymers are large molecules with high molecular weights (>1000 D). They have been underestimated for a long time as to their sensitizing capacities. Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still unknown. We report a case of allergic contact dermatitis to polyvinylpyrrolidone (PVP)/hexadecene copolymer in a purple-colored lipstick and review the literature on allergic contact dermatitis to 7 copolymers: PVP/hexadecene, PVP/eicosene, PVP/1-triacontene, methoxy polyethyleneglycol (PEG)-22/dodecyl glycols, methoxy PEG-17/dodecyl glycols, phthalic anhydride/ trimellitic anhydride/glycols, and polyvinyl methyl/maleic acid anhydride.

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Contact Dermatitis and Topical Agents

Cohen¹,

Price²,

Ramachandran³

2015

Cosmetic Dermatology

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Allergic contact dermatitis from phthalic anhydride/trimellitic anhydride/glycols copolymer in nail varnish

Cited by 30 publications

References 6 publications

Contact and primary irritant dermatitis of the nail unit diagnosis and treatment

Contact and primary irritant dermatitis of the nail unit diagnosis and treatment

Allergic contact dermatitis to copolymers in cosmetics – case report and review of the literature

Contact Dermatitis and Topical Agents

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