Allergic Contact Dermatitis to Fragrances. Part 1

Arribas, María Paloma; Soro, Pilar; Silvestre, J.F.

doi:10.1016/j.adengl.2012.01.022

Cited by 13 publications

(17 citation statements)

References 37 publications

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“…Fragrances are ubiquitous in the personal environment, and are found in cosmetic products (including shampoos, conditioners, soaps, deodorants, and make‐up), household goods (such as detergents, fabric softeners, air fresheners, cleaners, and polishes), topical medicaments, clothing, foods, and essential oils. Fragrances can even be found in cutting oil fluid . A recent survey found that, of 300 personal care and household products available in supermarkets, 89% contained fragrance chemicals .…”

mentioning

confidence: 99%

Fragrance allergy could be missed without patch testing with 26 individual fragrance allergens

et al. 2016

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confidence: 99%

Fragrance allergy could be missed without patch testing with 26 individual fragrance allergens

et al. 2016

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“…But they contain original fragrances. [8] The purpose of this study is to detect all the fragrance allergens which cause ACD.…”

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confidence: 99%

Analysis of hypersensitivity in fragrance series by patch testing

Periyasamy

Sekar

Rai

2019

Indian Dermatol Online J

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Introduction:Allergic contact dermatitis (ACD) is an inflammatory disorder, which occurs as a result of repeated contact with an allergen. Fragrances are the products obtained naturally or produced synthetically. The purpose of this study is to detect the fragrance allergens producing ACD.Materials and Methods:This is an open-label prospective observational study. Patients of age above 18 years with history of using cosmetic products with dermatitis lesions over face, neck, axilla and hands were included. Patch testing was done with fragrance series by using the standard technique. The results were interpreted on day 2 and day 4 as recommended by International Contact Dermatitis Research Group criteria.Results:Totally 27 patients were included in this study. Of them, 12 were males and 15 were females; the mean age was 43 years. The mean duration of symptoms was 12.5 months. The most common site of involvement was hands. Housewives and office workers were the most commonly affected occupational groups. The most commonly used category of cosmetic product was talcum powders by 13 (48.1%) patients. In this study, 85.18% patients showed at least one fragrance antigen positivity. Fragrance mix II is the most frequent allergen in this study.Discussion:We conclude that the fragrance mix II is an important marker to find out fragrance allergy. Hand dermatitis is the most common presentation in patients with fragrance allergy. Perfumed talcum powders, soaps and perfumes are the leading sources of sensitization to fragrance allergens.

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“… 3 Geographic variations may occur due to differences in the number of allergens tested and their concentrations, as well as to regional preferences for the use of certain fragrances. 4 , 5 …”

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confidence: 99%

“…Although the studies show that tests for FMI and balsam of Peru are effective in detecting 70% to 90% of the cases of ACD cause by fragrances, new markers have also gained inportance in the European series. 4 …”

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Positive results of patch tests with fragrance markers: analysis of a 15-year period at a Brazilian dermatology center

Hafner¹,

Munhoz²,

Jeldes³

et al. 2018

An. Bras. Dermatol.

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Fragrances may cause allergic contact dermatitis. Data on patients who were patch tested, between 2000 and 2015, with fragrance allergens included in the Brazilian baseline series (balsam of Peru, colophony and fragrance mix I), were collected and analyzed. Of these patients, 258 (13.8%) were positive for fragrance markers, 9.8% being positive for fragrance mix I. Among these 258 there was a predominance of women in their 40s, with hand eczema. The frequency of sensitization to fragrances, as well as the epidemiological profile, was supported by the literature. Fragrance mix I was the main marker. It is important to expand the fragrance markers used in the Brazilian baseline series of patch tests.

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Allergic Contact Dermatitis to Fragrances. Part 1

Cited by 13 publications

References 37 publications

Fragrance allergy could be missed without patch testing with 26 individual fragrance allergens

Fragrance allergy could be missed without patch testing with 26 individual fragrance allergens

Analysis of hypersensitivity in fragrance series by patch testing

Positive results of patch tests with fragrance markers: analysis of a 15-year period at a Brazilian dermatology center

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