Allergic contact dermatitis to Timolol

Allergic Contact Dermatitis in Children

“…The susceptibility to contact sensitization increases with the age. The most important allergens observed in this population are metals, mercury, pharmaceutical products and cosmetics (Vozmediano & Hita, 2005;Militello et al, 2006;Goossens & Morren, 2006;Jacob et al, 2008). ACD in childhood may also affect decisions regarding future occupations in adulthood.…”

“…Sensitization to contact allergens begins in infancy and continues to be more common in toddlers and young children (Seidenari et al, 1992;Giordano-Labadie et al, 1999;Vozmediano & Hita, 2005;Militello et al, 2006;Clayton et al, 2006;Garg et al, 2009;De Waard-van der Spek & Oranje, 2009), the age of sensitization can occur very early. In study of Bruckner et al (Bruckner et al, 2000), 45% of patients with positive reactions were younger than 18 months.…”

Allergic Contact Dermatitis in Children

“…Of these, about 56-93% was of current relevance (Weston & Weston, 1984;Pevny et al, 1984b;Fisher, 1994a;Rudzki & Rebandel, 1996;Stables et al, 1996;Manzini et al, 1998;Bruckner et al, 2000;Machovcová et al, 2001;Wöhrl et al, 2003;Heine et al, 2004;Lewis et al, 2004;Jøhnke et al, 2004;Vozmediano & Hita, 2005;Wahlberg & Lindberg, 2006;Goossens & Morren, 2006;Jacob et al, 2008). Among the children with a positive patch test 3.2% to 54.4% had multiple contact allergies (Mortz & Andersen, 1999).…”

Contact Dermatitis in Children

“…It is also thought to cross react with thimerosal, a compound that contains mercury. Sources of exposure include shoes in which mercury is used as a preservative, and more classically antiseptic solutions (Fernandez Vozmediano & Armario Hita, 2005). Other items that may contain mercurial agents are eye drops, depigmenting creams, pediculosis preparations, vaccines, broken thermometers, amalgam fillings, contact lens solutions and pesticides (Goossens & Morren, 2004).…”