Allergic contact sensitivity to gold with unusual features

Petros, Hoossik; Macmillan, Andrew

doi:10.1111/j.1365-2133.1973.tb15459.x

Cited by 46 publications

(5 citation statements)

References 9 publications

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“…In some cases deposits of gold have been found in the skin several years after therapy (10). Occasionally granulomatous skin lesions after contact with gold items or after skin tests have been described widi features consistent with pseudoiymphoma (11)(12)(13)(14)(15)(16)(17)(18)(19)(20).…”

Section: Discussionmentioning

confidence: 99%

Persistent cutaneous pseudolymphoma after intradermal gold injection

et al. 1996

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After intradermal testing with goldsodiumthiomalate (GSTM), 5 out of 8 patients developed skin papules at the test sites, which persisted up to 20 months. The lesions were surgically excised. Histology revealed pseudolymphoma of B and T cell type containing follicular structures and occasional small granulomas. The amount of histiocytic cells among B and T lymphocytes was pronounced, including acid cysteine proteinase inhibitor (ACPI) positive follicular dendritic cells, CD68 positive macrophages, factor XIIIa positive dermal dendrocytes and S-100 positive cells. By electron microscopy, the macrophages contained endosomes loaded with crystalloid material which contained gold in X-ray microanalysis. Atomic absorption spectrophotometry also confirmed the presence of gold in one specimen. Thus GSTM seemed to accumulate in tissue macrophages leading to constant immunologic activation with lymphoid proliferation and histiocytic response.

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Section: Discussionmentioning

confidence: 99%

Persistent cutaneous pseudolymphoma after intradermal gold injection

et al. 1996

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“…23 Papular eruption and keloid-like lesions have been noted as unusual features of gold allergy. 18,21,22 Allergic reaction to earrings presenting as itching, weeping, and soreness of the earlobe has been recognized and reported. 18 The reaction is a result of prolonged intimate contact with the dermatitis-producing metal, sometimes even after discontinuation.…”

Section: Resultsmentioning

confidence: 97%

“…18,21,22 Allergic reaction to earrings presenting as itching, weeping, and soreness of the earlobe has been recognized and reported. 18 The reaction is a result of prolonged intimate contact with the dermatitis-producing metal, sometimes even after discontinuation. The noneczematous manifestation is more prominent with gold allergy compared with the other metals.…”

Section: Resultsmentioning

confidence: 97%

The Mystery of the Split Earlobe

Raveendran

Amarasinghe

2004

Plastic and Reconstructive Surgery

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The ancient art of body piercing has rejuvenated in the recent years as part of the fashion process. The ear is the most frequent body part to be pierced to wear jewelry. Split earlobes are commonly presented to plastic surgeons and the recurrence rate is high. The etiology of the acquired split earlobe was thought to be attributable to either trauma or heavy earrings. In this study, the authors explored the cause of the split earlobe and recurrence after surgical repair. Twenty-five patients who were using gold earrings presented with split earlobe and were studied, and the etiology of the condition was analyzed. A questionnaire was completed and the tissue obtained during surgical repair of the split earlobes was submitted for histopathological studies. This group of patients was compared with 17 subjects having stretched earlobe who were using heavy gold earrings. The control group consists of 50 subjects using gold earrings with normal earlobes. Clinical presentation and the histological studies suggest that allergy to metals used in the earring could lead to split earlobe. There is a difference between the split earlobe and stretched earlobe; the latter results from constant pull by heavy earrings. The authors present a new theory regarding the etiology of split earlobe and recommend that avoiding the offending metal in the earring is indispensable to prevent recurrence.

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“…In their review of several European studies from 1972 to 1990, Reitschel and Fowler reported nickel allergy as the most common metal allergy, with a prevalence ranging from 7.3% to 17.4%, while cobalt's prevalence was somewhat lower at 4.6% to 7.7% (2). Nickel and gold have been reported as more prevalent causes of jewelry-related sensitization (3)(4)(5).…”

Section: Discussionmentioning

confidence: 99%