Allergic Reaction to an Amide Local Anaesthetic

Abstract

A 67-yr-old female patient gave a history of allergy to lignocaine. When she was challenge-tested with the intradermal injection of 0.5% bupivacaine 0.2ml she had a systemic reaction. This reaction was accompanied by a decrease in the concentration of complement C4 in the plasma, which indicated that the reaction was immunologically-mediated. This is the first report of allergy to a local anaesthetic drug which has been documented by concurrent immunological changes.

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“…, 2 Amongst the factors to be considered are the changes in middle ear pressure which occur both intra-and po~toperatively.~ We report a casc of acutc otic barotrauma associated with nitrous oxide anaesthesia.…”

Study -“Comparative Study of Combined Spinal Epidural Versus Epidural Anaesthesia in Lower Limb Surgeries And Lower Abdominal Surgeries ”

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