Allergic Reaction to Zirconia Ceramic Bridge Cementation Using a Dental Adhesive Resin Cement: a Case Report

Yamashiro, Keisuke; Miki, Haruna; Kitagawa, Masae; Oka, Hiroko; Arias, Zulema; Takashiba, Shogo

doi:10.1007/s42399-020-00671-9

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…Concerning biological criteria after 12 months, two patients in (Z) group reported slightly post hypersensitivity ( Table 1 and Diagram 2 ), which may be related to the use of a higher amount of pretreatment ceramic primer to ensure bond strength which got in contact with the patient's gingiva during the second cementation than during the first cementation ( Yamashiro et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Clinical outcome of CAD/CAM overlays of MIH affected young permanent molars

Eldehna,

Montaser,

ALrafee

et al. 2023

The Saudi Dental Journal

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Section: Discussionmentioning

confidence: 99%

Clinical outcome of CAD/CAM overlays of MIH affected young permanent molars

Eldehna,

Montaser,

ALrafee

et al. 2023

The Saudi Dental Journal

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“…Adhesive resin system 16 A patient experienced an adverse reaction following cementation of a zirconia bridge. Patch test results showed a positive allergic reaction to tooth primer light-cured adhesive resin Bonding agent 17 Three dental students in the USA each self-reported a rash after restoring a tooth with a composite and bonding system.…”

Section: Dental Materials Commentsmentioning

confidence: 99%

The safety and biocompatibility of direct aesthetic restorative materials

2022

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“…Acrylic monomers routinely used in dentistry have been known to cause allergic reactions in dental patients 1 , 2 . The release of acrylic monomers from bond-resin-based dental restorative materials causes local and systemic allergic reactions 3 , 4 . The monomer 2-hydroxyethyl methacrylate (HEMA) is a water-soluble acrylic resin monomer, is used in dental restorative procedures such as repair or restoration and root canal sealers, and is one of the main components in dentin bonding resins with contents varying from 30 to 55% 5 .…”

Section: Introductionmentioning

confidence: 99%

2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells

Orimoto

Kitamura

Ono

2022

Sci Rep

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Extracellular ATP (adenosine triphosphate) and transient receptor potential ankyrin 1 (TRPA1) channels are involved in calcium signaling in odontoblasts and dental pain. The resin monomer 2-hydroxyethyl methacrylate (HEMA), used in dental restorative procedures, is related to apoptotic cell death via oxidative stress. Although the TRPA1 channel is highly sensitive to reactive oxygen species (ROS), the effect of HEMA-induced ROS on ATP release to the extracellular space and the TRPA1 channel has not been clarified in human dental pulp. In this study, we investigated the extracellular ATP signaling and TRPA1 activation by HEMA-derived ROS in immortalized human dental pulp cells (hDPSC-K4DT). Among the ROS-sensitive TRP channels, TRPA1 expression was highest in undifferentiated hDPSC-K4DT cells, and its expression levels were further enhanced by osteogenic differentiation. In differentiated hDPSC-K4DT cells, 30 mM HEMA increased intracellular ROS production and ATP release, although 3 mM HEMA had no effect. Pretreatment with the free radical scavenger PBN (N-tert-butyl-α-phenylnitrone) or TRPA1 antagonist HC-030031 suppressed HEMA-induced responses. These results suggest that ROS production induced by a higher dose of HEMA activates the TRPA1 channel in human dental pulp cells, leading to ATP release. These findings may contribute to the understanding of the molecular and cellular pathogenesis of tertiary dentin formation and pain in response to dental biomaterials.

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Allergic Reaction to Zirconia Ceramic Bridge Cementation Using a Dental Adhesive Resin Cement: a Case Report

Cited by 3 publications

References 16 publications

Clinical outcome of CAD/CAM overlays of MIH affected young permanent molars

Clinical outcome of CAD/CAM overlays of MIH affected young permanent molars

The safety and biocompatibility of direct aesthetic restorative materials

2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells

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