Allergic Rhinitis and Chronic Daily Headaches: Is There a Link?

Gryglas, Anna

doi:10.1007/s11910-016-0631-z

Cited by 28 publications

(15 citation statements)

References 76 publications

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“…Asthma has also been indicated as a risk factor for new-onset chronic migraine [301][302][303]. In most of these studies, however, diagnosis of allergic disorders was not definitive and was solely based on the medical histories and allergic or respiratory symptoms, without spirometric confirmation.…”

Section: Epidemiological Evidencementioning

confidence: 99%

Headache and immunological/autoimmune disorders: a comprehensive review of available epidemiological evidence with insights on potential underlying mechanisms

Biscetti

Vanna

Cresta

et al. 2021

J Neuroinflammation

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Several lines of evidence support a role of the immune system in headache pathogenesis, with particular regard to migraine. Firstly, alterations in cytokine profile and in lymphocyte subsets have been reported in headache patients. Secondly, several genetic and environmental pathogenic factors seem to be frequently shared by headache and immunological/autoimmune diseases. Accordingly, immunological alterations in primary headaches, in particular in migraine, have been suggested to predispose some patients to the development of immunological and autoimmune diseases. On the other hand, pathogenic mechanisms underlying autoimmune disorders, in some cases, seem to favour the onset of headache. Therefore, an association between headache and immunological/autoimmune disorders has been thoroughly investigated in the last years. The knowledge of this possible association may have relevant implications in the clinical practice when deciding diagnostic and therapeutic approaches. The present review summarizes findings to date regarding the plausible relationship between headache and immunological/autoimmune disorders, starting from a description of immunological alteration of primary headaches, and moving onward to the evidence supporting a potential link between headache and each specific autoimmune/immunological disease.

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Section: Epidemiological Evidencementioning

confidence: 99%

Headache and immunological/autoimmune disorders: a comprehensive review of available epidemiological evidence with insights on potential underlying mechanisms

Biscetti

Vanna

Cresta

et al. 2021

J Neuroinflammation

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“…Almost 2% of the general population have chronic migraine; there is a significant socioeconomic impact on society, such as increased health care costs and decreased quality of life. The management of these headache patients should be a priority [15].…”

Section: Discussionmentioning

confidence: 99%

Turbinate Submucosal Reduction Operation Reduced Migraine Admission among Patients with Chronic Hypertrophic Rhinitis

Cheng

Chang

Cheng

et al. 2020

IJERPH

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Rhinitis increases migraine risk. Chronic hypertrophic rhinitis can be treated with turbinate submucosal reduction operation. The relationship between migraine and chronic hypertrophic rhinitis after turbinate submucosal reduction operation is still unclear. The goal of this study was to evaluate the correlation between turbinate submucosal reduction operation and subsequent migraine admission in Asian chronic hypertrophic rhinitis patients. We identified patients suffering from chronic hypertrophic rhinitis and receiving turbinate submucosal reduction operation. The control group was selected from patients with chronic hypertrophic rhinitis without operation. The event was migraine admission. The risk factors of migraine admission were established using multivariate Cox proportional hazard regression. The risk of migraine admission after turbinate submucosal reduction operation is represented by a hazard ratio (HR) of 0.858 (95% confidence interval (CI): 0.633–0.962). The higher risk of migraine included depression with HR 4.348 (95% CI: 2.826–6.69), anxiety with HR 3.75 (95% CI: 2.267–6.203), fibromyalgia with HR of 7.326 (95% CI: 3.427–15.661), and asthma with HR 1.969 (95% CI: 1.11–3.491). Our study revealed that turbinate submucosal reduction operation led to a 14.2% reduction in migraine admission. Clinicians should understand the benefit of turbinate submucosal reduction operation and provide suitable treatments for comorbid conditions. Further prospective studies are required to confirm our findings.

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“…The mechanism of type of headache effects the role of otorhinolaryngologist in identification, diagnosis, and treatment of the underlying causes. As the symptoms are overlapping for both sinugenic and non sinugenic headache or even exist simultaneously in the same patient more liberal diagnostic approach needed [6].…”

Section: Introductionmentioning

confidence: 99%

Comprehensive Role of Otorhinolaryngologists in the Management of Headache: A Prospective Tertiary Care Centre Based Study

Kamal¹

2021

OJCAM

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Background: Headache is most common complaint of human being. Classified into primary (migraine, tension headache and trigeminal neuralgia) and secondary (infectious, vascular and drug induced). Sinugenic headache is deep seated, dull aching with fullness and heaviness in sinus area. The purpose of study to assess the comprehensive role of otorhinolaryngologists in the diagnosis of headache and to evaluate the efficacy of medical and surgical management of patients presented with headache. 200 patients reported to rhinology clinic with headache. Detailed history, head and neck examination routine blood investigation, fundus examination & anterior rhinoscopy, radiological investigations X-ray paranasal sinuses, skull & cervical spine and direct nasal endoscopy was and CT paranasal sinus preoperatively done.Results: 200 patients assessed using VAS analog scale before and after treatment dividing into four groups: resolved, improved, no change, and worsened' group; p value was statistically significant in resolved and improved group whereas non-significant in no change and worsened group. 129 patients had non-sinugenic headache; 29(22.48%) with cervical cause, Migraine 24 (18.60%) and ophthalmic 23 (17.48%) respectively; dental and vascular 19 (14.72%) each, and psychogenic headache in 13 (10.07%) and trigeminal neuralgia in 2 patients (1.55%). 96.12 % were relieved by medical treatment whereas 71 patients of sinugenic headache 21.12% were treated successfully with medical treatment. One refused surgery, 50/55 (90.90%). Improvement assessed by SNOTT-22 pre-and post-surgery that was statistically significant p value-0.002. Conclusion:Headache need comprehensive management. Sinugenic headache managed successfully initially with medical treatment and refractory cases by surgical intervention with equal efficacy.

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Allergic Rhinitis and Chronic Daily Headaches: Is There a Link?

Cited by 28 publications

References 76 publications

Headache and immunological/autoimmune disorders: a comprehensive review of available epidemiological evidence with insights on potential underlying mechanisms

Headache and immunological/autoimmune disorders: a comprehensive review of available epidemiological evidence with insights on potential underlying mechanisms

Turbinate Submucosal Reduction Operation Reduced Migraine Admission among Patients with Chronic Hypertrophic Rhinitis

Comprehensive Role of Otorhinolaryngologists in the Management of Headache: A Prospective Tertiary Care Centre Based Study

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