Allergic sensitization of the skin and nails to acrylic plastic nails

Acrylate allergy induced by acrylic nails resulting in prosthesis failure

“…The clinical manifestations of allergic contact dermatitis secondary to cutaneous contact with acrylate monomers include eczematous dermatitis, paronychia, onycholysis, parathesias, and/or onychial and paronychial pain. 11,12 Intraorally, pronounced erythema and edema may occur, as can the development of a lichenoid dermatitis adjacent to the dental acrylate. This report emphasizes the fact that sensitization to acrylates used in acrylic nail products may place patients at risk for aseptic loosening of joints following orthopedic prostheses that require bone cement.…”

Safety and Efficacy of Nail Products

“…Findings such as paronychia and subungual swelling, severe pruritus, nail dystrophy, and scaling/vesicular dermatitis were noted. In one case, a "moth-eaten" appearance of the nail was described with slight separation of the nails from the nail bed [41]. In these older cases, acrylic monomers were suspected to be the offending agent, however the specific monomers could not be confirmed.…”

“…As early as the 1940s and 1950s, cases of ACD due to acrylic nails were noted [40,41]. Findings such as paronychia and subungual swelling, severe pruritus, nail dystrophy, and scaling/vesicular dermatitis were noted.…”

“…More distal findings have been reported as well, likely due to hand transfer-related contact allergy or occupational exposure. The face, and particularly the eyelids, are commonly involved [21,31,41,44,48,51,54,55]. A case of cheilitis and lip edema in the setting of contact with UV-cured gel nails was reported.…”

Subjective symptoms among dental technicians exposed to the monomer methyl methacrylate.

“…One o f the mo st used chemic als is th e monomer methyl methacr ylate. There are man y reports on th e adverse effects of th is chemical (2,8,9,10,II,19).…”