Allium sativum and Group B Streptococcus: antimicrobial and synergistic activity

Abstract

Objective The study aimed to evaluate the antimicrobial activity of the SP80 fraction (obtained from Allium sativum) and its synergism with the antibiotic against strains of GBS. Methods The broth microdilution and disk diffusion assays were used to determine the antimicrobial and synergistic activity of Sep-pak 80% (SP80) in combination with ampicillin and penicillin G, respectively. Results The results showed that the combination of SP80 and antibiotics respectively showed an additive effect. Conclusions The SP80 fraction has antimicrobial activity against GBS, and the association with the antibiotic has an additive effect.