2024
DOI: 10.3390/hematolrep16040077
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Alloantibody Identification: The Importance of Temperature, Strength Reaction and Enzymes—A Practical Approach

Palma Manduzio

Abstract: Red blood cell (RBC) alloimmunization and antibodies formation against non-self antigens on red cells may occur after blood transfusion, pregnancies or other exposures. The RBC alloimmunization rate varies from 2% to 6% according to recent studies. The antibody screen is performed to identify or confirm the presence of antibodies in patient’s serum or plasma, as a preoperative or pretransfusion test. The antibody identification process and major crossmatch are critical steps of risk management in transfusion m… Show more

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