Allogeneic Blood Transfusion Is a Significant Risk Factor for Surgical-Site Infection Following Total Hip and Knee Arthroplasty: A Meta-Analysis

Kim, Jeong Lae; Park, Jong Hoon; Han, Seung Beom; Cho, Il Youp; Jang, Ki-Mo

doi:10.1016/j.arth.2016.08.026

Cited by 176 publications

(107 citation statements)

References 30 publications

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“…A recent meta-analysis reported a prevalence of SSI of 2.88% in patients who undergo TJA and received an allogenic blood transfusion compared with 1.74% among those who did not. 70 This supports earlier studies that showed a two-fold greater risk for PJI in patients who have a transfusion. 71,72 Pre-operative screening of haemoglobin levels and the use of erythropoietin aim to maximise the levels of haemoglobin.…”

Section: Post-operative Measuressupporting

confidence: 90%

Prevention of periprosthetic joint infection

Parvızı

Shohat

Gehrke

2017

The Bone & Joint Journal

149

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The World Health Organization (WHO) and the Centre for Disease Control and Prevention (CDC) recently published guidelines for the prevention of surgical site infection. The WHO guidelines, if implemented worldwide, could have an immense impact on our practices and those of the CDC have implications for healthcare policy in the United States. Our aim was to review the strategies for prevention of periprosthetic joint infection in light of these and other recent guidelines. Cite this article: Bone Joint J 2017;99-B(4 Supple B):3–10.

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Section: Post-operative Measuressupporting

confidence: 90%

Prevention of periprosthetic joint infection

Parvızı

Shohat

Gehrke

2017

The Bone & Joint Journal

149

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“…Second, over 80% of the increase in RBC usage concerns patients undergoing orthopedic and cardiac surgeries. For orthopedic surgery, the increase can simply be explained by a relevant increase in the number of patients treated (842 vs. 1250 patients), because the mean number of units transfused for each patients did not change (2.6 vs. 2.5 units), nor did the transfusion rate, which remained approximately 20%, comparable to data from the literature . For heart surgery, there was an important shift in the type of surgery: although the total number of patients in this group was lower in Period 2, the number of procedures with a greater risk of blood loss was markedly higher.…”

Section: Discussionmentioning

confidence: 51%

Electronic remote blood issue combined with a computer‐controlled, automated refrigerator for major surgery in operating theatres at a distance from the transfusion service

et al. 2017

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“…For example, inconsistent use of blood products during various surgical procedures, including coronary artery bypass grafting, has heightened scrutiny over the appropriateness of transfusion across medical and surgical procedures . Recent studies also have described an association between liberal transfusion policies and increased incidence of health care‐associated infections, including surgical site infections and sepsis . Other studies have implicated high PLT dosing as a risk factor for transfusion‐associated adverse events, and transfusions in patients with certain gastrointestinal and other metastatic diseases may be associated with reduced chances of remission and survival .…”

Section: Discussionmentioning

confidence: 99%

Continued decline in blood collection and transfusion in the United States–2015

et al. 2017

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BACKGROUND In 2011 and 2013, the National Blood Collection and Utilization Survey (NBCUS) revealed declines in blood collection and transfusion in the United States. The objective of this study was to describe blood services in 2015. STUDY DESIGN AND METHODS The 2015 NBCUS was distributed to all US blood collection centers, all hospitals performing at least 1000 surgeries annually, and a 40% random sample of hospitals performing 100 to 999 surgeries annually. Weighting and imputation were used to generate national estimates for units of blood and components collected, deferred, distributed, transfused, and outdated. RESULTS Response rates for the 2015 NBCUS were 78.4% for blood collection centers and 73.9% for transfusing hospitals. In 2015, 12,591,000 units of red blood cells (RBCs) (95% confidence interval [CI], 11,985,000‐13,197,000 units of RBCs) were collected, and 11,349,000 (95% CI, 10,592,000‐11,747,000) were transfused, representing declines since 2013 of 11.6% and 13.9%, respectively. Total platelet units distributed (2,436,000; 95% CI, 2,230,000‐2,642,000) and transfused (1,983,000; 95% CI, 1,816,000 = 2,151,000) declined by 0.5% and 13.1%, respectively, since 2013. Plasma distributions (3,714,000; 95% CI, 3,306,000‐4,121,000) and transfusions (2,727,000; 95% CI, 2,594,000‐2,859,000) in 2015 declined since 2013. The median price paid per unit in 2015—$211 for leukocyte‐reduced RBCs, $524 for apheresis platelets, and $54 for fresh frozen plasma—was less for all components than in 2013. CONCLUSIONS The 2015 NBCUS findings suggest that continued declines in demand for blood products resulted in fewer units collected and distributed Maintaining a blood inventory sufficient to meet routine and emergent demands will require further monitoring and understanding of these trends.

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Allogeneic Blood Transfusion Is a Significant Risk Factor for Surgical-Site Infection Following Total Hip and Knee Arthroplasty: A Meta-Analysis

Cited by 176 publications

References 30 publications

Prevention of periprosthetic joint infection

Prevention of periprosthetic joint infection

Electronic remote blood issue combined with a computer‐controlled, automated refrigerator for major surgery in operating theatres at a distance from the transfusion service

Continued decline in blood collection and transfusion in the United States–2015

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