Allogeneic Hematopoietic Cell Transplantation in the Outpatient Setting

Outpatient allogeneic hematopoietic stem-cell transplantation: a review

“…Facing difficulties regarding institutions in Mexico and other LMICs, where developing a traditional HSCT unit is usually unrealistic and accompanied by economical, social and technical complications, outpatient HSTC emerges as an affordable, safe, and realistic option for patients dwelling in LMIC. 40 , 42 The results of outpatient transplantation have never been directly compared with in-hospital procedures. However, reported experience has demonstrated feasibility.…”

“…9,32 solve many common issues that arise during HSCT and avoid (or facilitate) hospitalization allowing that team to deliver IV fluids for dehydration, antiemetics, transfusions, and/or antibiotics while monitoring patients for several hours a day. 40 This day hospital can work 5-7 days a week in a standard or extended schedule according to different centers; 41,42 however, the fundamental issue is the ability to provide emergency care either in the clinic itself or in the emergency room for care out of clinic hours to decide if the patient will be sent home with appropriate therapy or admitted to the inpatient unit. If an emergency department admission is needed, once the patient arrives is managed in an isolated room.…”

Management of early period of hematopoietic cell transplantation in ambulatory/outpatient setting with primary antimicrobial prophylaxis: an attractive option

“…If necessary, a patient staying at home should have immediate access to hospital facilities not only in an Outpatient Clinic, but also within night-time coverage by a physician available after hours in the system of inpatient setting [8,9].…”