Allogenic Cord Blood Transfusion in Preterm Infants

Teofili, Luciana; Papacci, Patrizia; Giannantonio, Carmen; Bianchi, Maria; Giovanna Valentini, Caterina; Vento, Giovanni

doi:10.1016/j.clp.2023.07.005

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article4

Preprint1

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Banked term umbilical cord blood to meet the packed red blood cell transfusion needs of extremely-low-gestational-age neonates: a feasibility analysis

Christensen,

Bahr,

Christensen

et al. 2023

J Perinatol

View full text Add to dashboard Cite

OBJECTIVES: To assess the feasibility of drawing, processing, safety-testing, and banking term umbilical cord blood to meet the packed red blood cell transfusion (RBC Tx) needs of extremely-low-gestational-age neonates (ELGANs).DESIGN: 1) Retrospectively analyze all ELGANs RBC Tx over the past three years, 2) Estimate local cord blood availability, 3) Assess interest in this project, and implementation barriers, through stakeholder surveys.RESULTS: In three years we cared for 266 ELGANs; 165 (62%) received ≥1 RBC Tx. Annual RBC Tx averaged 197 (95% CI, 152 -243). If 10% of our 10,353 annual term births had cord blood drawn and processed, and half of those tested were acceptable for Tx, collections would exceed the 95 th % upper estimate for need by >four-fold. Interest exceeded 97%. Identi ed barriers included FDA approval, training to collect cord blood, and cost. CONCLUSION: RBC Tx needs of ELGANS could be met by local cord blood collection.

show abstract