Alopecia areata: An update

Seetharam, K A

doi:10.4103/0378-6323.116725

Cited by 90 publications

(104 citation statements)

References 86 publications

(165 reference statements)

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“…AA is among the most common forms of nonscarring alopecia [35]. The broadest study on trichoscopy of AA was performed by Lacarrubba et al [2], Ross et al [5] and Inui [21].…”

Section: Discussionmentioning

confidence: 99%

Clinical, Histological and Trichoscopic Correlations in Scalp Disorders

et al. 2015

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Trichoscopy is the term coined for the dermoscopic imaging of scalp and hair. This diagnostic technique, simple and noninvasive, can be used as a handy bedside tool for the diagnosis and follow-up of hair and scalp disorders. It allows the recognition of morphologic structures not visible by the naked eye and provides the clinician with a range of dermoscopic findings necessary for differential diagnosis. Trichoscopy observation can be broadly grouped as interfollicular patterns and follicular patterns. Recently, a third mixed class, called the follicular plus interfollicular pattern, has been introduced. Some of these features are specific to a certain scalp disease, while others can be found in many hair disorders. Although studies suggest that the use of trichoscopy can improve clinical accuracy, further investigation is needed. This review provides update information on the trichoscopic features of the most common scalp disorders, striving to show a histopathological and clinical correlation.

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“…AA is among the most common forms of nonscarring alopecia [35]. The broadest study on trichoscopy of AA was performed by Lacarrubba et al [2], Ross et al [5] and Inui [21].…”

Section: Discussionmentioning

confidence: 99%

Clinical, Histological and Trichoscopic Correlations in Scalp Disorders

et al. 2015

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“…In general, the younger the age of the patient at onset and more widespread the disease, the poorer is the prognosis [21,22]. Spontaneous hair regrowth, however, has been observed more frequently in single AA patches [23].…”

Section: Rycina 7 Wyniki Leczenia W Zależności Od Czasu Trwania Chorobymentioning

confidence: 99%

Original papers A study on efficacy of 308 nm excimer light therapy in alopecia areata

Sanga¹,

Mittal²

2015

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Introduction. Alopecia areata (AA) is an autoimmune condition characterized by T-cell-mediated attack on hair follicles.Objective. Evaluation of efficacy of 308 nm excimer light in the treatment of alopecia areata. Material and methods.Patches of AA were treated twice weekly, but not on 2 consecutive days, with UVB excimer 308 nm light. In all patients, half of the AA patch was irradiated and the other half was spared, covered with a black rubber shield and taken as a control. Therapy was started with an initial dose of 300 mJ/cm 2 , with an incremental dose of 100 mJ/cm 2 at every sitting until fine erythema appeared.Results. At the end of the treatment, one patient (3.33%) at the test site showed > 50% hair regrowth vs. none at the control site. After a 2-month post-treatment period, successful hair regrowth (grades 3 and 4) was seen in 12 patients at test sites and in 2 patients at control sites. The differences were statistically significant (p < 0.05). After 4 months successful hair regrowth (grades 3 and 4) was seen in 16 patients at test sites and in 5 patients at control sites. The differences were statistically significant (p < 0.05). There was no statistically significant difference in the response to treatment in relation to the duration of the disease (p > 0.05). Conclusions.Excimer light has the potential to stimulate hair regrowth in patches of alopecia areata.streszczenie Wprowadzenie. Łysienie plackowate (alopecia areata -AA) jest chorobą autoimmunologiczną charakteryzującą się atakiem limfocytów T na mieszek włosowy. Cel pracy. Ocena skuteczności światła ekscymerowego w terapii pojedynczych ognisk AA. Materiał i metodyka.Ogniska AA naświetlano 2 razy w tygodniu (ale nie w kolejnych dniach) promieniowaniem ekscymerowym (UVB) o długości fali 308 nm. U wszystkich pacjentów napromieniowywano jedną połowę ogniska, natomiast druga, osłonięta czarną gumą, służyła jako kontrola. Naświetlania rozpoczynano od dawki 300 mJ/cm 2 , którą zwiększano o 100 mJ/cm 2 podczas kolejnych naświetlań aż do uzyskania wyraźnego rumienia.A study on efficacy of 308 nm excimer light therapy in alopecia areata badania nad skutecznością promieniowania ekscymerowego o długości fali 308 nm w leczeniu łysienia plackowatego zo nun sanga, Asit Mittal

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“…The youngest patient we saw was 2 year old and oldest patient we saw was 60 year old. Seetharaman et al 15 in their study saw the age range of these patients from 4 months to 70 years. In our study, alopecia areata was the most common type of alopecia seen (89.65%).…”

Section: Discussionmentioning

confidence: 99%