Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases

Eckert, Marta Mendieta; Gundin, Nerea Landa; Crespo, Raquel Lambea

doi:10.4172/2471-9323.1000108

Cited by 14 publications

(17 citation statements)

References 18 publications

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“…Other associated conditions with alopecia areata include atopic dermatitis, celiac disease, pernicious anemia, psoriasis, rheumatoid arthritis, systemic lupus erythematosus, and vitiligo [3,4]. Multiple therapies have been identified as effective treatments for beard alopecia areata ( Table 1) [3][4][5][6][7][8][9][10][11][12][13][14]. Treatment with corticosteroids (either intralesional or topical) is usually the first line of therapy.…”

Section: Discussionmentioning

confidence: 99%

“…Immunosuppressants [5,7], CR Corticosteroids (intralesional injections, topical) [5,7], CR Immunotherapy [6] Anthralin and diphenylcyclopropenone [6] Janus kinase (JAK) inhibitors [3,8,9] Ruxolitinib [8] Tofacitinib [3,9] Laser [10][11][12] 308-nm excimer laser [10] 908-nm diode laser [11] 1,550-nm fractional laser [12] Minoxidil [7] Photodynamic therapy [13] Platelet-rich plasma (PRP) [14] Prostaglandin F2-alpha analogues [7] Latanoprost [7] Treatment of concurrent Helicobacter pylori infection [4] Our patient decided to treat his beard alopecia areata with topical 0.1% triamcinolone acetonide cream. This led to a complete regrowth of his beard hair within six months.…”

Section: Treatment Referencesmentioning

confidence: 99%

“…Light therapy has also been investigated for the treatment of hair loss. The use of lasers or photosensitive agents and light can lead to hair regrowth in beard alopecia areata [10][11][12][13].…”

Section: Treatment Referencesmentioning

confidence: 99%

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Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review of Alopecia Areata of the Beard

Forouzan

Cohen²

2020

Cureus

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Alopecia areata is a non-scarring hair loss that commonly presents on the scalp. In men, when this condition results in facial hair loss on the cheek, jaw, and neck, it is referred to as beard alopecia areata. Beard alopecia areata can be associated with autoimmune conditions, such as diabetes mellitus, thyroid disorders, and vitiligo. A 28-year-old man presented with a fivemonth history of facial hair loss; his condition was diagnosed as beard alopecia areata after clinical examination. Treatment with twice daily topical 0.1% triamcinolone acetonide cream led to complete regrowth of his beard hair after six months. There are several potential agents and modalities for the treatment of individuals with beard alopecia areata. Treatment options include corticosteroid therapy (intralesional or topical), immunotherapy, Janus kinase (JAK) inhibitors, lasers, photodynamic therapy, platelet-rich plasma therapy, and treatment of an underlying Helicobacter pylori infection. Laboratory evaluation, prompted by our patient's diagnosis of beard alopecia areata, suggested incipient diabetes mellitus and nascent thyroid disease; specifically, he had elevated fasting blood glucose and elevated thyroid-stimulating hormone levels. Therefore, in patients with beard alopecia areata, laboratory evaluation for concomitant or incipient autoimmune diseases should be considered.

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Section: Discussionmentioning

confidence: 99%

Section: Treatment Referencesmentioning

confidence: 99%

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Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review of Alopecia Areata of the Beard

Forouzan

Cohen²

2020

Cureus

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“…All patients obtained fully or almost fully regrowth at 3 months, without any side effects except for minimal pain during the treatment. 28 The possible mechanisms hypothesized for fractional photothermolysis laser in hair regrowth are the induction of T-cell apoptosis and direct enhancement of hair growth. 27 In addition, the therapeutic effects of the laser have been proven in larger number of patients with androgenic alopecia, 29,30 but since the exact mechanisms of hair regrowth is unknown, the elucidation of the pathophysiology is necessary.…”

Section: Fractional Non-ablative Photothermolysis Lasermentioning

confidence: 99%

“…A recent study has also reported the efficacy of erbium glass laser in five patients with AA. 28 The patients were treated for 2 to 3 sessions, with an interval of 3-6 weeks and the parameters of fluences ranging from 30-45 mJ/cm 2 , 6-8 density and 8-10 passes. All patients obtained fully or almost fully regrowth at 3 months, without any side effects except for minimal pain during the treatment.…”

Section: Fractional Non-ablative Photothermolysis Lasermentioning

confidence: 99%

Use of Lasers in the Treatment of Alopecia Areata

Chu

Kim

2016

Medical Lasers

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Alopecia areata (AA) is a complex autoimmune disease characterized by round or oval patches of non-scarring hair loss that is mediated by lymphocytes affecting the hair follicles. To treat localized AA, intralesional corticosteroid injections and topical corticosteroids are most commonly used, while for widespread AA, systemic steroids, immunosuppresants, and contact immunotherapy are commonly considered. However, therapeutic options for refractory AA that is unresponsive to these conventional treatments are limited. Various lasers have been suggested in recent studies to treat AA. The effect of 308-nm excimer laser was the most studied, while others, including neodymium-doped yttrium aluminum garnet, erbium:glass laser, fractional CO2 laser, and low-level laser therapy, have also been assessed. Despite the nascent state of research on lasers as a treatment option for AA, there have been a great deal of promising results. It is possible for lasers to become the mainstay treatment option of AA. Key words

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The Use of a 1,540 nm Fractional Erbium‐Glass Laser in Treatment of Alopecia Areata

Al‐Dhalimi

Al-janabi

2019

Lasers Surg Med

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Background and Objectives Varieties of laser and light sources have been tried for treatment of alopecia areata (AA) and some success has been reported. To assess the effectiveness of 1,540 nm fractional erbium‐glass laser in treatment of AA. Study Design/Materials and Methods The patches of AA were divided into two groups, the study group (I) underwent six sessions of laser therapy at weekly interval with topical minoxidil solution applied twice daily for 6 weeks, while group (II), the control group was received only topical minoxidil solution. The patches were evaluated objectively (hair count and percentage of regrowth) and subjectively (patient satisfaction) at the end of follow‐up period (another 6 weeks). Results The percentage of hair increment between pre‐treatment and follow‐up period was 30% for study patches versus 6.45% for control patches. Regarding the percentage of growth, the response rate for study patches was 60% versus 16% for the control. Conclusions Erbium‐glass laser seems to be effective in regrowing hair in AA. The durability of the response is unknown. Possible mechanisms of improvement include the induction of a thermal effect on papillary dermis, which stimulates hair regrowth, or an immunological effect on the follicle. In addition, the erbium‐glass laser may enhance the delivery of minoxidil solution. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.

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Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases

Cited by 14 publications

References 18 publications

Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review of Alopecia Areata of the Beard

Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review of Alopecia Areata of the Beard

Use of Lasers in the Treatment of Alopecia Areata

The Use of a 1,540 nm Fractional Erbium‐Glass Laser in Treatment of Alopecia Areata

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