Alpha-fetoprotein levels in placenta, maternal, and cord blood in normal and pathologic pregnancy

Fk, Khalil; Bonnet, M; Guibaud, S; Combet, A; Jm, Thoulon; Durmont, M

doi:10.1097/00006250-197907000-00026

“…All the bags tested, apart from the Air-Viva, produced satisfactory results at both tidal volumes with zero carbon dioxide during the inspiratory phase (figure). With the Air-Viva, however, the inspired carbon dioxide concentration rose immediately-that is, rebreathing occurred-and after [20][21][22][23][24][25][26][27][28][29][30] seconds reached a plateau of 2%, which was then maintained throughout the five and 15 minute periods. Increasing the tidal volume did not influence this rise in inspired carbon dioxide.…”

Section: Methods and Resultsmentioning

confidence: 99%

Case-Control Study of Severe Pre-eclampsia of Early Onset

Moore

¹

,

Redman

²

1984

Obstetrical & Gynecological Survey

View full text Add to dashboard Cite

Twenty four women with severe pre-eclampsia diagnosed before 34 weeks' gestation were compared with 48 randomly selected controls matched for age and parity. Subjects were studied in the puerperium using a questionnaire, clinical examination, and review of case records. A history of infertility, headaches (particularly migraine), pre-eclampsia in a previous pregnancy, or a raised serum a-fetoprotein concentration at the time of screenri ing for neural tube defect in the index pregnancy were all identified as significant risk factors in the pre-eclamptic women. Maternal age, a history of chronic hypertension or renal disease, or excessive maternal weight were not significantly associated with pre-eclampsia. Almost all the infants of pre-eclamptic women showed retarded growth: 18 were below the 10th centile and only one weighed more than the 25th centile. Four babies died.These observations indicate that pre-eclampsia of early onset may differ from the late onset disease not only in its very high perinatal morbidity and mortality but in its distinctive maternal risk factors.

show abstract

“…Secondly, the family histories of hypertension and other arterial disease did not differ. Nine pre-eclamptic women (38%,) compared with 17 controls TABIE i-Age, parity, blood pressure, and plasma urate concentrations in preeclamptic and normal women Control Pre-eclampiia (n = 48) (n = 24) Mean age, in years (range) 26 (35°)) gave a family history of hypertension in parents or siblings. Similarly, coronary artery and cerebrovascular disease were equally common in families of both groups.…”

Section: Resultsmentioning

confidence: 99%

Case-control study of severe pre-eclampsia of early onset.

Moore¹,

Redman²

1983

BMJ

View full text Add to dashboard Cite

Twenty four women with severe pre-eclampsia diagnosed before 34 weeks' gestation were compared with 48 randomly selected controls matched for age and parity. Subjects were studied in the puerperium using a questionnaire, clinical examination, and review of case records. A history of infertility, headaches (particularly migraine), pre-eclampsia in a previous pregnancy, or a raised serum a-fetoprotein concentration at the time of screenri ing for neural tube defect in the index pregnancy were all identified as significant risk factors in the pre-eclamptic women. Maternal age, a history of chronic hypertension or renal disease, or excessive maternal weight were not significantly associated with pre-eclampsia. Almost all the infants of pre-eclamptic women showed retarded growth: 18 were below the 10th centile and only one weighed more than the 25th centile. Four babies died.These observations indicate that pre-eclampsia of early onset may differ from the late onset disease not only in its very high perinatal morbidity and mortality but in its distinctive maternal risk factors.

show abstract

Maternal serum alfa‐fetoprotein levels in the pregnancy complicated by hypertension

Clayton-Hopkins

¹

,

Olsen

²

,

Blake

³

1982

View full text Add to dashboard Cite

Maternal serum alpha-fetoprotein (MSAFP) was determined in patients 33 to 40 weeks pregnant, and the Iesults were analysed with consideration of the presence and quality of hypertensive disease that complicated many of the pregnancies. Patients with incompletely controlled hypertension had significantly higher MSAFP levels than control patients with pregnancies uncomplicated by any risk factor. MSAFP elevation was greatest in pre-eclampsia (301.6 k 147.6 kU/L, n = 35) >chronic hypertension with superimposed pre-eclampsia (240.4 f 74.7 kU/L, n = 30) > chronic hypertension (204.1 f 105.3 kU/L, n = 141). Each was significantly increased (P< 0.0001) over control pregnant patients' levels (104.3 f 38.8, n= 187). At each gestational week from 33 weeks to term, MSAFP of combined hypertensive women was significantly greater than corresponding control levels (P < 0.003 to < 0-Oool).The magnitude and time of onset of MSAFP increase may indicate severe fetal distress.

show abstract

Alpha-fetoprotein levels in placenta, maternal, and cord blood in normal and pathologic pregnancy

Cited by 4 publications

References 0 publications

Case-Control Study of Severe Pre-eclampsia of Early Onset

Case-Control Study of Severe Pre-eclampsia of Early Onset

Case-control study of severe pre-eclampsia of early onset.

Maternal serum alfa‐fetoprotein levels in the pregnancy complicated by hypertension

Contact Info

Product

Resources

About