Alpha‐momorcharin preserves catalase activity to inhibit viral infection by disrupting the 2b–CAT interaction in <i>Solanum lycopersicum</i>

Yang, Ting; Peng, Qiao; Lin, Honghui; Xi, Dehui

doi:10.1111/mpp.13279

Cited by 8 publications

(6 citation statements)

References 57 publications

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“…Our previous work on the interaction between Nicotiana tabacum and chili veinal mottle virus (ChiVMV), a virus that causes symptoms of systemic necrosis on tobacco, showed that overexpression of CAT1 can enhance the resistance of N. tabacum and inhibit the infection of ChiVMV (Yang et al, 2020). In another study, we found that alpha‐momorcharin could disrupt the interaction between cucumber mosaic virus (CMV) 2b and CATs and preserve CAT activity to relieve the symptoms of necrosis caused by viral infections in Solanum lycopersicum (Yang et al, 2023). However, the roles of CATs of tobacco plants in response to the infection of compatible viruses remain unclear.…”

Section: Introductionmentioning

confidence: 99%

Catalases mediate tobacco resistance to virus infection through crosstalk between salicylic acid and auxin signaling pathways

Huang,

Jiao,

et al. 2023

Physiologia Plantarum

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Catalases (CATs) play important roles in plant growth, development and defense responses. Previous studies have shown that CATs exhibit different or even opposite effects on plant immunity in different plant–pathogen interactions, but little is known about the mechanisms. In this study, Nicotiana tabacum plants with overexpression or knockout of CAT genes, tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) were employed to investigate the role of CAT in compatible plant–virus interactions. The results showed that there were dynamic changes in the effect of CAT on N. tabacum defense responses. Overexpression of catalase 1 (CAT1) and catalase 3 (CAT3) improved N. tabacum resistance in the early stage of virus infection but depressed it during the late stages of pathogenesis, especially in CAT3 overexpressing plants. The lower level of electrolyte leakage, lower contents of malonaldehyde and hydrogen peroxide (H2O2), higher activities of antioxidant enzymes and improved functions of photosystem II corresponded to the milder symptoms and higher resistance of infected tobacco plants. In addition, the infection of TMV and CMV resulted in expression changes of CATs in tobacco plants, and pretreatment with H2O2 facilitated TMV and CMV infection. Further experiments showed that the content of salicylic acid (SA) and the expression of genes related to SA signaling pathway were positively correlated with plant resistance, whereas auxin and its related signaling pathway were related to the viral susceptibility of plants. Taken together, our results demonstrated that CAT1 and CAT3 mediated tobacco resistance to virus infection through crosstalk between SA and auxin signaling pathways.

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Section: Introductionmentioning

confidence: 99%

Catalases mediate tobacco resistance to virus infection through crosstalk between salicylic acid and auxin signaling pathways

Huang,

Jiao,

et al. 2023

Physiologia Plantarum

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“…Cycas-fed animals had a reduced level of SOD activity when compared with the control (P < 0.05). Catalase is an enzymatic antioxidant that catalyzes the decomposition of hydrogen peroxide to oxygen and water, thereby curtailing oxidative damage and stress produced during the harmful oxidation process (Lolodi and Eriyamremu, 2013;Yang et al, 2023). Since catalase is a key enzyme for the resistance to oxidative stress, therefore a decrease in catalase activity suggests that they are generally downregulated in tumour tissues compared with normal cells.…”

Section: Discussionmentioning

confidence: 99%

COMPARATIVE STUDY FOR RESPONSE TO Cycas circinalis-INDUCED TOXICITY IN LIVER, KIDNEY AND COLON OF RATS AND GUINEA PIGS

OLUDE,

OMOREGIE

2024

AJHSE

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This study evaluated the toxicological response of rats and guinea pigs to Cycas in feed. Ten rats and guinea pigs were randomly designated into two groups for each animal. The control groups were fed with a normal diet while the experimental groups were fed with the Cycas-containing feed for 6 weeks. The effect of the Cycas feed on the animals’ liver, kidney, and colon were evaluated using biochemical and histological assays. The result of the experiment showed changes in body weight and tissue (liver, kidney, and colon) antioxidant levels. Additionally, the animals on the Cycas diet observed an increase in oxidative stress and lipid peroxidation. The histology result for both the rats and guinea pigs revealed that cycasin present in the plant is a potent colon carcinogen, it induced hyperplasia in the colon cells which is a great pointer towards abnormal cell division and hence cancer. We predicted that the plant via its induction of oxidative damage and depletion of tissue antioxidants could drive tissue toward tumorigenesis in both animals. There were significant changes between the (p<0.05) values derived from the different animals. Guinea pigs were more susceptible to the negative effects of the cycasin.

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“…The detection of the purified recombinant SmCAT4-GST or GST proteins was performed following a previously described study [69].…”

Section: Recombinant Cat Enzyme Assaymentioning

confidence: 99%

Genome-Wide Identification of Catalase Gene Family and the Function of SmCAT4 in Eggplant Response to Salt Stress

Shen,

Xia,

Zhang

et al. 2023

IJMS

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Salinity is an important abiotic stress, damaging plant tissues by causing a burst of reactive oxygen species (ROS). Catalase (CAT) enzyme coded by Catalase (CAT) genes are potent in reducing harmful ROS and hydrogen peroxide (H2O2) produced. Herein, we performed bioinformatics and functional characterization of four SmCAT genes, retrieved from the eggplant genome database. Evolutionary analysis CAT genes revealed that they are divided into subgroups I and II. The RT-qPCR analysis of SmCAT displayed a differential expression pattern in response to abiotic stresses. All the CAT proteins of eggplant were localized in the peroxisome, except for SmCAT4, which localized in the cytomembrane and nucleus. Silencing of SmCAT4 compromised the tolerance of eggplant to salt stress. Suppressed expression levels of salt stress defense related genes SmTAS14 and SmDHN1, as well as increase of H2O2 content and decrease of CAT enzyme activity was observed in the SmCAT4 silenced eggplants. Our data provided insightful knowledge of CAT gene family in eggplant. Positive regulation of eggplant response to salinity by SmCAT4 provides resource for future breeding programs.

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Alpha‐momorcharin preserves catalase activity to inhibit viral infection by disrupting the 2b–CAT interaction in Solanum lycopersicum

Cited by 8 publications

References 57 publications

Catalases mediate tobacco resistance to virus infection through crosstalk between salicylic acid and auxin signaling pathways

Catalases mediate tobacco resistance to virus infection through crosstalk between salicylic acid and auxin signaling pathways

COMPARATIVE STUDY FOR RESPONSE TO Cycas circinalis-INDUCED TOXICITY IN LIVER, KIDNEY AND COLON OF RATS AND GUINEA PIGS

Genome-Wide Identification of Catalase Gene Family and the Function of SmCAT4 in Eggplant Response to Salt Stress

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