Alpha‐thalassemia. Case report alpha‐thalassemia in a Costa Rican family, A case report

Abstract

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The need to perform α‐thalassemia genetic testing in Italian patients with β‐thalassemia trait: A case report

“…Genetic testing for both thalassemias is recommended in areas where malaria was endemic, as in some regions of Italy like Sardinia, but also in regions of Italy where internal immigrations from regions with high incidence of thalassemias or immigrations from developing countries where hemoglobinopathies are more frequent, particularly from Mediterranean area, Indian Sub‐Continent and South‐East Asia, were increased in the last decades, like Lombardy. This could be useful not only for prenatal screening program 2 or to make a differential diagnosis with thalassemia due to iron defiency, 5 but also for family counseling, to assess β‐thalassemia risk and to avoid the potential risk of HbH disease in case of marriage between the proband, α + carrier, with a α° partner.…”