Alphafetoprotein levels in amniotic fluid from 8 to 18 weeks of pregnancy

Wathen, N. C.; Campbell, D. J.; Kitau, M. J.; Chard, Tim

doi:10.1111/j.1471-0528.1993.tb12984.x

Cited by 15 publications

(6 citation statements)

References 11 publications

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“…Prenatal alpha-fetoprotein level (MU/L). Alpha-fetoprotein (AFP) is thought to be a general marker for severe fetal ill health and also provides a specific control for any unexpected abnormalities of amniotic fluid dilution (Wathen, Campbell, Kitau, & Chard, 1993). Amniotic AFP levels were also assayed by the Department of Clinical Biochemistry, Addenbrooke's Hospital, Cambridge, England (see Appendix B).…”

Section: Predictor Variablesmentioning

confidence: 99%

Gender-Typed Play and Amniotic Testosterone.

Knickmeyer¹,

Wheelwright²,

Taylor³

et al. 2005

Developmental Psychology

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Sex differences in play are apparent in a number of mammalian species, including humans. Prenatal testosterone may contribute to these differences. The authors report the first attempt to correlate gender-typed play in a normative sample of humans with measurements of amniotic testosterone (aT). Testosterone was measured in the amniotic fluid of 53 children (31 boys and 22 girls). A strong sex difference was observed in aT and, at ages 4.75 to 5.8 years, on a modified version of the Child Game Participation Questionnaire. Hierarchical regression analyses on the entire group and within-sex correlations suggested that variations in aT did not contribute to individual differences in game participation as reported by the mother. A critique of explanations for this finding is presented.

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Section: Predictor Variablesmentioning

confidence: 99%

Gender-Typed Play and Amniotic Testosterone.

Knickmeyer¹,

Wheelwright²,

Taylor³

et al. 2005

Developmental Psychology

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“…Prenatal alpha‐foetoprotein level. Alpha‐foetoprotein (AFP) is thought to be a general marker for severe foetal ill‐health and also provides a specific control for any unexpected abnormalities of amniotic fluid dilution (Wathen, Campbell, Kitau, & Chard, 1993).…”

mentioning

confidence: 99%

Foetal testosterone, social relationships, and restricted interests in children

Knickmeyer

Baron‐Cohen

Raggatt

et al. 2004

Child Psychology Psychiatry

235

156

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“…Entre las semanas 8 y 13 de gestación se dan cambios muy rápidos en los niveles de AFP en el líquido amniótico por lo que es muy difícil la interpretación clínica de esta medición y muy dependiente del cálculo de la edad gestacional de la paciente (16).…”

Section: Discussionunclassified

Utilidad de la alfa-fetoproteína en el diagnóstico prenatal de defectos del tubo neural y anomalías cromosómicas

Salas-Chaves¹,

Rodríguez-Aguilar²,

Cunningham-Lucas³

et al. 2003

Rev Biomed

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Recibido el 9/Noviembre/2001. Aceptado para publicación el 12/Julio/2002. Este artículo está disponible en http://www.uady.mx/~biomedic/rb031413.pdf Artículo Original Rev Biomed 2003; 14:5-10. Artemisa medigraphic en línea 6 Revista Biomédica P Salas-Chaves, S Rodríguez-Aguilar, L Cunningham-Lucas, I Castro-Volio. SUMMARY.Utility of the alpha-fetoprotein in the prenatal diagnosis of neural tube defects and chromosomal abnormalities. Introduction. The present study focuses on the utility of AFP in prenatal diagnosis of 96 Costa Rican pregnant women. Material and methods. In these women, genetic amniocentesis and AFP levels were done between the 15 th and 25 th week of gestation. There were two main reasons for referral: abnormal ultrasound assessment and advanced maternal age. Results. The concentration values of AFP were expressed as multiples of the median, considering a value of 2.5 MoM as a normal superior limit and of 0.25 as the inferior limit. The confidence limits of the median were 562-1196 KU/l and the 2.5MoM value was located between 1404-2989 KU/l. Four cases had AFP levels higher than the median: one case of Turner Syndrome, another case of encephalocele and two normal karyotypes. Four other cases had AFP levels lower than 0.25 MoM: a case of trisomy 21, a case of trisomy 18, a case of omphalocele and a normal karyotype. Discussion. Prenatal diagnosis of fetal defects allowed genetic counseling as well as better obstetric management and pediatric care. (Rev Biomed 2003; 14:5-10)

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Alphafetoprotein levels in amniotic fluid from 8 to 18 weeks of pregnancy

Cited by 15 publications

References 11 publications

Gender-Typed Play and Amniotic Testosterone.

Gender-Typed Play and Amniotic Testosterone.

Foetal testosterone, social relationships, and restricted interests in children

Utilidad de la alfa-fetoproteína en el diagnóstico prenatal de defectos del tubo neural y anomalías cromosómicas

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