Alteraciones inmunológicas asociadas a parotiditis crónica recurrente juvenil

Hidalgo-Santos, Antonio David; Gastón-Téllez, Rubén; Ferrer-Lorente, Begoña; Pina-Pérez, Raquel; Oltra-Benavent, Manuel

doi:10.1016/j.anpedi.2020.08.007

Cited by 6 publications

(4 citation statements)

References 16 publications

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“…The first episode of parotitis is often attributed to mumps, in addition to mumps, other viruses such as epstein-barr virus (EBV), parainfluenza, adenovirus, human herpes virus type 6 (HHV-6), [ 23 ] hepatitis C virus [ 24 ], and HIV [ 25 ] have been implicated.…”

Section: Discussionmentioning

confidence: 99%

“…JIRP could be considered a warning sign of potential selective IgA deficiency, IgG subclass deficiencies, gastrointestinal disorders (especially coeliac disease), autoimmune diseases and even malignant tumors [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

“…JIRP could be a new indicator to rule out coeliac disease and routine screening for coeliac disease should be tested in these patients [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

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Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Salehzadeh,

Molatefi,

Mardi

et al. 2024

Pediatr Rheumatol

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Background Juvenile idiopathic recurrent parotitis (JIRP) in children is a condition characterized with recurrent episodes of idiopathic parotid gland inflammation. Since there are no definitive guidelines for diagnosis and management of this condition, we present a consecutive case series of patients with more than one decade follow up and their dramatic response to short course treatment by prednisolone. Methods We conducted this study by retrospectively reviewed medical charts of children who were diagnosed with JIRP, from 1 January 2002 to 29 February 2023. We performed usual serological tests to exclude some possible background. We administered short course prednisolone on first day of episode as divided dosage (0.5 mg /kg). Results In this case series of 10 patients (70%) were male, median age of onset was 5 years, duration of episodes 5 days, and the mean course of disease were 3.8 years. The average follows up of patients was near 10 years. In comparison with their natural course of disease all patients showed a dramatic response to treatment on the first day of administration of prednisolone (P Value 0.005). For ten years follow up there was not any additional accompanying autoimmune disorder. Conclusion Short course prednisolone on first day of each episode and its dramatic and meaningful response in our patients, introduce a new, effective, fast, and inexpensive regimen of therapy in patients with JIRP.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Salehzadeh,

Molatefi,

Mardi

et al. 2024

Pediatr Rheumatol

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“…JIRP could be a new indicator to rule out coeliac disease and routine screening for coeliac disease should be tested in these patients. (25) Two retrospectively large series report among the pediatric patients identi ed, 1 positive test for antithyroglobulin antibodies, and 2 increased levels of ANA, and 1 levels of IgG and IgM in the lower limit of normal, 1 decreased levels of IgA, 2 cases increased levels of IgE. ( ( 28, 4)…”

Section: Discussionmentioning

confidence: 99%

Juvenile Idiopathic Recurrent Parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Salehzadeh,

Molatefi,

Mardi

et al. 2023

Preprint

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Background: Juvenile idiopathic recurrent parotitis (JIRP) in children is a condition characterized with recurrent episodes of idiopathic parotid gland inflammation. Since there are no definitive guidelines for diagnosis and management of this condition, we determined to present a consecutive case series of patients with more than one decade follow up and their dramatic response to short course treatment by prednisolone. Methods: We conducted this study twenty years ago, however we retrospectively reviewed medical charts of children who were diagnosed with JIRP, from 1 January 2002 to 29 February 2023. We performed usual serological tests to exclude some possible background. We administered short course prednisolone on first day of episode as divided dosage (0.5 mg /kg). Results: In this case series 7 patients (70%) were male, median age of onset was 5 years, duration of episodes 5 days, and the course of disease were 3.8 years. The average follow up of patients was near 10 years. In comparison with their natural course of disease all patients showed a dramatic response to treatment on the first day of administration of prednisolone (P Value 0.005).During ten years follow up there was not any additional accompanying autoimmune disorder. Conclusion: Short course prednisolone on first day of each episodes and its dramatic and meaningful response in JIRP, introduce effective, fast, somehow safe, and inexpensive regimen of therapy in these patients.

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Utility of sialendoscopy in the management of juvenile recurrent parotitis. Retrospective study

Andueza Guembe,

Chiesa Estomba,

Saga Gutiérrez

et al. 2024

Acta Otorrinolaringologica (English Edition)

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Alteraciones inmunológicas asociadas a parotiditis crónica recurrente juvenil

Cited by 6 publications

References 16 publications

Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Juvenile Idiopathic Recurrent Parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder

Utility of sialendoscopy in the management of juvenile recurrent parotitis. Retrospective study

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