Alterações cutâneas secundárias à infecção por leishmania sp.: revisão de literatura

Azevedo, Roberta Carvalho de Freitas e; Marcili, Arlei

doi:10.34117/bjdv6n4-195

Cited by 7 publications

(8 citation statements)

References 13 publications

(33 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Concerning the clinical aspects, among symptomatic dogs, classic clinical alterations of leishmaniasis such as alopecia, onychogryphosis, lymphadenomegaly, and ear tip lesions were observed (Moreira et al 2016 ; Contreras et al 2019 ; Azevedo and Marcili 2020 ; Pasanisi 2020 ). Furthermore, the ocular form of CanL was also observed in these dogs, in which changes such as periocular alopecia, blepharitis, keratitis, and conjunctivitis are among the most reported ophthalmic and clinical manifestations are consequences of systemic impairment caused by Leishmania, which involves direct mechanisms of tissue damage due to the presence of the parasite and specific cytotoxic immune responses.…”

Section: Discussionmentioning

confidence: 99%

Canine leishmaniasis in an endemic region, Northeastern Brazil: a comparative study with four groups of animals

et al. 2021

View full text Add to dashboard Cite

Canine leishmaniasis (CanL) is a zoonosis caused by protozoa of the genus Leishmania and remains an important public health concern in tropical areas. In Brazil, domestic dogs are considered the most relevant reservoir of the parasite and one of the main targets of the disease control actions. Considering this, we aimed herein to evaluate the CanL infection in different canine groups and distribution of cases in the state of Sergipe, an endemic region in Northeastern Brazil. The evaluated 467 animals were classified into four groups: hunting ( n = 50), company ( n = 64), guard ( n = 140), and wandering ( n = 213). Samples (blood, bone marrow, conjunctival swab, and lymph node aspirate) were collected from animals in nine municipalities of Sergipe. First, all animals were submitted to general and ophthalmic clinical examination. Next, they were tested serologically by TR-DPP®, and for the presence of Leishmania , amastigotes in samples of bone marrow, conjunctival swab, and lymph node aspirate were diagnosed by PCR and parasitological techniques. It was observed that 34.69% (162) of the evaluated dogs were seropositive. The highest rates of positivity were found in hunting 54% (27/50; OR = 3.52; p -value = 0.001) and guard dogs 42.14% (59/140; OR = 2.18; p -value = 0.01). Otherwise, the highest percentage of symptomatic dogs was observed in wandering animals (85%; OR = 9.63; p -value < 0.0001). The distribution of case analysis showed that the highest positivity rates occurred in inland municipalities situated in arid regions. Taken together, our data demonstrate that hunting and guard dogs are among the animals most exposed and affected by clinical manifestations of CanL, mainly in the inland municipalities of Sergipe State. Supplementary Information The online version contains supplementary material available at 10.1007/s00436-021-07319-0.

show abstract

Section: Discussionmentioning

confidence: 99%

Canine leishmaniasis in an endemic region, Northeastern Brazil: a comparative study with four groups of animals

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Com relação às dermatopatias, essas ocorrem em mais de 80% dos casos de LVC, sendo muitas vezes a principal queixa clínica [3]. São descritos na LVC os padrões dermatológicos esfoliativo, ulcerativo e nodular, sendo mais comuns os padrões esfoliativo e ulcerativo [20,29].…”

Section: Discussionunclassified

“…Inicialmente, para tratamento tópico foi prescrito colírio à base de acetato de prednisolona a 1% (Pred Fort ®1 -BID, até novas recomendações), xampu manipulado à base de peróxido de benzoíla a 2% e ácido salicílico 2% para banhos uma vez por semana até novas recomendações e também uso de ômega 3 Desta forma, devido a não haver a possibilidade de terapia na época, foi realizada a eutanásia do paciente com posterior análise necroscópica. O resultado da necropsia evidenciou as seguintes alterações macroscópicas: seborreia no tegumento, principalmente na região dorso-caudal, lesões crostosas no pavilhão auricular esquerdo, congestão e edema nos pulmões, linfoadenomegalia dos linfonodos pré escapulares, poplíteos e mandibulares, esplenomegalia associado a inflamação crônica, hepatomegalia associada a edema e congestão, hidronefrose no rim esquerdo, hiperemia e opacidade da córnea e fibrose da região da dura máter.…”

Section: Introductionunclassified

See 1 more Smart Citation

Visceral Leishmaniasis in Dogs

Silveira

Mendes

Pereira

et al. 2021

Acta Scientiae. Vet.

View full text Add to dashboard Cite

Background: Canine visceral leishmaniasis (CVL) is a zoonosis of variable clinical presentation, either in systemic or cutaneous form. Clinical signs include anorexia, ophthalmopathies, and chronic kidney disease. In the state of Santa Catarina, the foci are concentrated in the capital and its adjacencies, in the east side of the state. The objective of this study is to outline the first three reported cases of CVL in the municipality of Curitibanos, since there are no reports to date in the region of the mountainous plateau, in the middle west of Santa Catarina.Cases: All dogs were treated at the Veterinary Clinic School of the Federal University of Santa Catarina, Campus Curitibanos. The animals, two males and one female, belonged to the same tutor, resided in Curitibanos, and were attended between 2016 and 2020. In the first case, attended in 2016, the complaint was of eye and skin changes about three months ago. The animal lived in an urban environment and came from Uruguaiana, Rio Grande do Sul. On physical examination, the animal presented skin peeling, wet and crusty lesions, bloody discharge in the ears and nasal hyperkeratosis, as well as signs suggestive of uveitis. In this case, euthanasia was carried out. The second case had complaints of respiratory, eye changes, hyporexia, and polydipsia. The dog was prostrate, dehydrated, with lymphadenomegaly and respiratory disorders, compatible with bacterial pneumonia. Bilateral corneal edema confirmed uveitis. Upon return, the animal remained dehydrated with enlarged lymph nodes. In the aspiration of the lymph nodes, suggestive forms of Leishmania sp. were observed. The recommended confirmatory tests were performed, leading to a definitive diagnosis of CVL. The patient was treated with miltefosine, but later died. The third case was attended for general evaluation after a positive diagnosis for CVL during an epidemiological survey of the second case. The animal was alert, tachycardic, and tachypneic with hyperemic mucous membranes. Miltefosine-based treatment and permanent use of deltamethrin-impregnated collar were prescribed and ovariohysterectomy was carried out. The patient is clinically well. In the search for vectors, in no place or moment of search, referring to the cases, vectors for CVL were found.Discussion: It is suggested that patients 2 and 3 are autochthonous cases, whose transmission form has not been fully elucidated, and vector transmission cannot be ruled out, as well as other less common forms of transmission. For case 1, it is suggested that it is an allochthone case, probably imported from the Uruguaiana region, where the disease is endemic. The conduct of a positive result for CVL is euthanasia, with the exception of dogs that have guardians who wish to perform treatment, but not always possible due to the high cost of miltefosine, the only drug approved for dog therapy in Brazil. In the first case, the owner opted for euthanasia, since in 2016 there was no possibility of treatment. For the last two cases, a treatment cycle was performed as recommended by the guidelines. Regarding the municipality of Curitibanos, in the first case diagnosed in 2016, the animal came from Uruguaiana. In conclusion, this study aimed to report the clinical and epidemiological characteristics related to the first three patients with CVL reported in Curitibanos.

show abstract

“…Embora seja apontada como uma doença tropical negligenciada, oriunda de regiões pobres, estima-se que mais de 350 milhões de pessoas estejam susceptíveis aos riscos destas infecções, que cursam na maioria das vezes com espectro clínico grave (ALVAR et al, 2006;VRIES et al, 2015;EL HAJJ et al, 2018). No Brasil é reconhecido o envolvimento de mais de cinco espécies do gênero Leishmania, das quais, duas estão incorporadas ao subgênero Leishmania: Leishmania (L.) infantum e Leishmania (L.) amazonensis; e pelo menos seis no subgênero Viannia: Leishmania (V.) guyanensis, Leishmania (V.) lainsoni, Leishmania (V.) shawi, Leishmania (V.) naiffi, Leishmania (V.) lindenbergi e Leishmania (V.) braziliensis (SILVA et al, 2008;LAINSON, 2010;AZEVEDO;MARCILI, 2020).…”

Section: Introductionunclassified

Leishmaniose Ocular Canina: Uma Revisão Das Manifestações Clínicas, Diagnóstico E Tratamento

Oliveira¹,

Neto²,

Silva³

et al. 2022

Atualidades Na Saúde E Bem-Estar Animal, Volume 6

View full text Add to dashboard Cite

Esta obra está licenciada com uma Licença Creative Commons Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo desta obra e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Editor Chefe Atualidades na Saúde e Bem-Estar Animal, Volume 6 3 APRESENTAÇÃO O sexto volume desta obra é dirigido para aqueles que precisam das informações essenciais e atuais sobre a saúde das diversas espécies animais, bem como o seu bem-estar, abrangendo diversas áreas da medicina veterinária e zootecnia. Procuramos fornecer os fatos clínicos mais importantes, assim como estratégias de manejo animal para uma maior efetividade e produtividade proveniente do bem-estar animal.Nós oferecemos nesta obra uma apresentação baseada em trabalhos realizados na patologia animal, patologia clínica, clínica médica, reprodução e produção animal, genética e bem-estar, tanto nas espécies domésticas como nas espécies silvestres.Os diversos trabalhos publicados nesta obra relatam da importância do bem-estar animal, o acometimento de espécies não domiciliadas com patologias majoritariamente urbanas, manejo animal e revisões de literatura atuais sobre diversos assuntos da clínica médica para auxiliar em um melhor entendimento e conduta clínica do médico veterinário, afim de promover uma melhor qualidade de vida aos animais e proporcionar um maior conhecimento sobre a prevenção, controle e diagnóstico dessas doenças.Esperamos que este volume seja útil a todos os que estejam à procura de uma literatura concisa sobre a saúde animal e, consequentemente, seu bem-estar como base para estudos médicos veterinários e áreas afins que corroboram com o tema.

show abstract

Alterações cutâneas secundárias à infecção por leishmania sp.: revisão de literatura

Abstract: Alterações cutâneas secundárias à infecção por leishmania sp.: revisão de literatura Skin disturbs caused by leishmania sp. Infection: review

Cited by 7 publications

References 13 publications

Canine leishmaniasis in an endemic region, Northeastern Brazil: a comparative study with four groups of animals

Canine leishmaniasis in an endemic region, Northeastern Brazil: a comparative study with four groups of animals

Visceral Leishmaniasis in Dogs

Leishmaniose Ocular Canina: Uma Revisão Das Manifestações Clínicas, Diagnóstico E Tratamento

Contact Info

Product

Resources

About