Alteration of cardiac autonomic functions in patients with major depression: A study using heart rate variability measures

Cardiac autonomic dysfunction assessed by heart rate variability in major depression

“…Udupa et al [3] have reported no significant correlation between severity of depression and autonomic parameters. Contrary to our results, this finding may be because of newly diagnosed patients of depression in their study where the duration of the diseased state was not known and probably patients were not having long standing MDD.…”

“…Very few studies have been carried out to assess cardiac autonomic functions in depressed patients in Indian population. [3,4] The extent of autonomic function derangement also needs to be assessed along with any possible correlation of degree of autonomic dysfunction with the severity of depressive disorder. Conflicting results are available about correlation of autonomic dysfunction and severity of depression.…”

“…Conflicting results are available about correlation of autonomic dysfunction and severity of depression. [3,5] Thus, there is a need to add more research data on HRV in this group of patients, particularly in Indian population.…”

Electrocardiographic Analysis of Heart Rate Variability in Aging Heart

“…The right anterior insula has a role in modulation of sympathetic tone and is implicated in the sympathetic arousal associated with mental tasks. Major depression and depressive symptoms are associated with decreased HRV, both in patients with coronary heart disease (Carney et al, 2001;Vigo et al, 2004) and in community subjects (Udupa et al, 2007;van der Kooy et al, 2006). Depression has been associated with increased risk of morbidity and mortality in patients with coronary artery disease (Lett et al, 2004).…”

Autonomic Dysfunction in Major Depressive Disorder

“…There are conflict of reports on results of low LF power, HF power and higher LF/HF both in medicated and drug naive depressed patients 8 .…”