Alteration of Cardiac Output During Induced Hypotension

Schenk, Worthington G.; Menno, Albert D.; Little, David M.

doi:10.1097/00132586-196206000-00032

Cited by 2 publications

(3 citation statements)

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“…The decrease of arterial pressure in the two groups was also comparable. No decrease of the cardiac output occurs within the limits of the fall in pressure that was achieved (Schenk & Menno, 1961), and arterial pressure during the infusion remained within the normal range of renal autoregulation. Increases or mild modifications of RPF, GFR, urinary volume and sodium excretion were recorded during trimetaphan administration in patients ofgroup A, and the renogram remained unchanged.…”

Section: Discussionmentioning

confidence: 85%

Assessment of Renal Function during Trimetaphan Infusion in Prognostic Evaluation of Surgical Management of Renovascular Hypertension

Fiorani¹,

Faraglia²,

Benedetti-Valentini³

et al. 1971

Clinical Science

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1. Differential renal function tests and renography were carried out during infusions oftrimetaphan camsylate (Arfonad, Roche) in twenty-three patients with renovascular hypertension resulting from unilateral obstructive disease of the main renal artery. Renal plasma flow, glomerular filtration rate, urinary volume and sodium excretion were measured. Peak-time and slope index were assessed on renograms. Ten patients underwent revascularization of the kidney; nephrectomy was done in thirteen.2. Patients were divided into two groups according to the response of the contralateral kidney during trimetaphan infusion. Patients in whom vasodilatation occurred were cured both by revascularization and by nephrectomy, whereas no patient who failed to show vasodilatation was benefited by nephrectomy.3. Renal plasma flow measured under basal conditions was not a reliable index of the anatomical condition of the contralateral kidney, whereas its modification during trimetaphan infusion provided an accurate means of predicting surgical results.4. When renal plasma flow of the contralateral kidney decreases during trimetaphan infusion, revascularization is still advisable, but nephrectomy fails to correct hypertension.The results of surgery in renovascular hypertension (R VH) due to unilateral renal artery disease depend, among other factors, on the anatomical and functional status of the contralateral kidney. This may be explored by means of differential renal function tests or histological study of a needle-biopsy specimen. Kincaid-Smith (1966), Hood (1966), Peart (1966 and Tcherdakoff (1966) have pointed out, however, that a renal biopsy may fail to demonstrate vascular pathology which is present in another portion of the kidney, and histology shows a static picture which makes it difficult to assess the significance and possible reversibility of lesions of the renal arterioles. Yutani,

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Section: Discussionmentioning

confidence: 85%

Assessment of Renal Function during Trimetaphan Infusion in Prognostic Evaluation of Surgical Management of Renovascular Hypertension

Fiorani¹,

Faraglia²,

Benedetti-Valentini³

et al. 1971

Clinical Science

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“…Greenfield (1957) says, 'Whether or not a steady (ie., non-pulsatile) pressure is haemodynamically equivalent to each of the family of fluctuating intra-arterial pressures of which it is the mean is at best doubtful.' Others (Schenk, Menno, and Crowe, 1962) go further when they say: 'The "steady" state in which mean values are utilized, simply does not exist within the vascular tree'; they do later admit that mean values are acceptable where pulsation is not excessive, if only for the calculation of cardiac work. Even Greenfield (1957) regards the use of mean pressure data as 'a simple and probably reasonable approximation to the truth'.…”

Section: Discussionmentioning

confidence: 99%

“…The massive bulk of alternating current theory has been drawn on to help explain some of the features of a flow of blood which is undoubtedly pulsatile. More refined methods of pulse-wave analysis are now available with the use of computers (Schenk, Menno, and Crowe, 1962;Taylor, 1962), which in this field yield much accurate information.…”

Section: The Values Of Series and Parallel Resistances In Steady Bloomentioning

confidence: 99%

The values of series and parallel resistances in steady blood-flow

Weale¹

1964

Journal of British Surgery

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Alteration of Cardiac Output During Induced Hypotension

Cited by 2 publications

References 0 publications

Assessment of Renal Function during Trimetaphan Infusion in Prognostic Evaluation of Surgical Management of Renovascular Hypertension

Assessment of Renal Function during Trimetaphan Infusion in Prognostic Evaluation of Surgical Management of Renovascular Hypertension

The values of series and parallel resistances in steady blood-flow

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