Alteration of occlusal vertical dimension induces signs of neuroplastic changes in corticomotor control of masseter muscles: Preliminary findings

Deng, Hongkui; Gao, Shang; Lu, Shengyi; Kumar, Abhishek; Zhang, Zhenting; Svensson, Peter

doi:10.1111/joor.12682

Cited by 18 publications

(15 citation statements)

References 59 publications

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“…Contemporary orofacial neuroscience [60] related research has emphasized the importance of sensorimotor regulation [61][62][63][64][65][66][67][68][69][70] and adaptation to the altered oral environment during biting [64,[71][72][73][74] and chewing behaviors [71]. Further, recent studies have discussed the significance of retaining natural dentition and optimizing oral functions in people with a dental prosthesis [62,63,[75][76][77][78].…”

Section: Discussionmentioning

confidence: 99%

Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study

et al. 2021

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Background Epidemiological studies show an association between masticatory function and cognitive impairment. This has further strengthened the notion that tooth loss and impaired masticatory function may be risk factors for dementia and cognitive decline. Animal experiments have indicated a causal relationship and several possible mechanisms have been discussed. This evidence is, however, lacking in humans. Therefore, in the current interventional study, we aim to investigate the effect of rehabilitation of masticatory function on cognition in older adults. Methods Eighty patients indicated for prosthodontic rehabilitation will be randomly assigned to an experimental or a control group. Participants will conduct neuropsychological assessments, masticatory performance tests, saliva tests, optional magnetic resonance imaging, and answer questionnaires on oral health impact profiles and hospital anxiety and depression scale before, 3 months, and 1 year after oral rehabilitation. The difference between the two groups is that the control group will be tested an additional time, (at an interval of about 3 months) before the onset of the oral rehabilitation procedure. The primary outcome is a change in measures of episodic memory performance. Discussion Although tooth loss and masticatory function are widespread in older people, it is still an underexplored modifiable risk factor potentially contributing to the development of cognitive impairment. If rehabilitation of masticatory function shows positive effects on the neurocognitive function, this will have great implications on future health care for patients with impaired masticatory status. The present project may provide a new avenue for the prevention of cognitive decline in older individuals. Trial registration: The protocol for the study was retrospectively registered in ClinicalTrials.gov Identifier: NCT04458207, dated 02-07-2020.

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Section: Discussionmentioning

confidence: 99%

Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study

et al. 2021

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“…15,16 On the other hand, OVD increase in patients with severe attrition induces signs of neuroplastic changes in corticomotor control of masseter muscles. 17 Therefore, when alteration in OVD is planned for patients with TMD, two-step approach is suggested regardless of the amount of increase. 10 The patient in the present case stated a dubious dental anamnesis about TMD-associated symptoms.…”

Section: Discussionmentioning

confidence: 99%

Rehabilitation of a Severely Worn Dentition with Partial Lithium-disilicate Glass Ceramic Restorations: A Case Report

Oğuz¹,

Berksun²

2021

EADS

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Rehabilitation of worn dentition is a challenging task because several predisposing factors may be included in the pathogenesis. The treatment options and process should be carefully considered based on the clinical condition and patients’ requirements. This case report represents the esthetic rehabilitation of a 68-year-old patient who exhibited severely worn teeth caused by attrition and erosion. After clinical evaluation, 3 mm increase in occlusal vertical dimension was planned with partial lithium-disilicate ceramic restorations as laminate veneers for anterior teeth and vonlays (onlays with veneer extentions) for posterior teeth in maxilla. The adaptation of the patient to the increased occlusal vertical dimension was tested for 1 month by provisional direct composite restorations. As the patient did not show any discomfort, definitive restorations were completed. The patient was satisfied with the esthetics and functionality of her new dentition.

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“…Alterations in the input/output curve over time may be due to changes of the excitation distribution in the corticospinal system or of the spatial distribution of excitatory elements in the cortex 30 . The alteration in the COG of motor representation maps suggests the reorganisation of the primary control area in the cortex 37,38 . If no component of learning or skill acquisition is involved, the motor representation maps do not extend; alterations in orthodontic treatment are not enough to cause the recombination reflected by the motor cortex mapping 3,36,39 …”

Section: Discussionmentioning

confidence: 99%

Changes of neuroplasticity in cortical motor control of human masseter muscle related to orthodontic treatment

Liu

Cui

et al. 2021

J of Oral Rehabilitation

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Background Orthodontic treatment is a common clinical method of malocclusion. Studies have found that neurons in the sensorimotor cortex of the brain undergo adaptive remodeling in response to changes in oral behavior or occlusion. Objective To explore whether orthodontic treatment could be sufficient to cause neuroplastic changes in the corticomotor excitability of the masseter muscle. Methods Fifteen Angle Class II malocclusion patients who were receiving orthodontic treatment participated in the study. Cortical excitability was assessed by electromyographic activity changes evoked by transcranial magnetic stimulation. Four orthodontic time points were recorded, including baseline, day 1, day 7, and day 30. Motor evoked potentials (MEPs) were recorded in the masseter muscle and the first dorsal interosseous muscle (FDI) serving as a control. The data were analysed by stimulus–response curves and corticomotor mapping. Statistical analyses involved repeated measures analysis of variance, two‐way ANOVA, and Tukey's post hoc tests. Results Motor evoked potentials (MEPs) of the masseter muscle were significantly decreased during orthodontic treatment compared with those of the baseline (p < .001). MEPs of the masseter muscle were dependent on session and stimulus intensity (p < .001), whereas MEPs of FDI were only dependent on stimulus intensity (p = .091). Finally, Tukey's post hoc tests demonstrated that MEPs of the masseter muscle on days 1 and 7, with 70%–90% stimulus intensities, were higher than those of baseline values (p < .001). Conclusions The present study suggested that orthodontic treatment can lead to neuroplastic changes in the corticomotor control of the masseter muscle, which may add to our understanding of the adaptive response of subjects to changes of oral environment during the orthodontic treatment.

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Alteration of occlusal vertical dimension induces signs of neuroplastic changes in corticomotor control of masseter muscles: Preliminary findings

Cited by 18 publications

References 59 publications

Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study

Cognitive changes and neural correlates after oral rehabilitation procedures in older adults: a protocol for an interventional study

Rehabilitation of a Severely Worn Dentition with Partial Lithium-disilicate Glass Ceramic Restorations: A Case Report

Changes of neuroplasticity in cortical motor control of human masseter muscle related to orthodontic treatment

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