Alteration of Phenotypic Characteristics of Burkholderia Pseudomallei During Interaction With Tetrahymena Pyriformis

Korol, Evgenia; Welfare, Human; Merinova, L K; Plekhanova, N. G.; Меринова, О А; Шубникова, Е. В.; Сенина, Т. В.

doi:10.19163/1994-9480-2018-2(66)-44-46

Journal of Volgograd State Medical University

2018

DOI: 10.19163/1994-9480-2018-2(66)-44-46

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Alteration of Phenotypic Characteristics of Burkholderia Pseudomallei During Interaction With Tetrahymena Pyriformis

Evgenia Korol¹,

Human Welfare²,

L K Merinova³

et al.

Abstract: Проведен пассаж культуры возбудителя мелиоидоза, Burkholderia pseudomallei, в клетках Tetrahymena pyriformis. Установлена способность микроорганизма к выживанию и размножению в простейших. После пассажа в тетрахименах отмечено увеличение продукции внеклеточных ферментов, подвижности и снижение вирулентности культур.

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Modern Condition of Siberian Tick Typhus Foci

Рудаков¹,

Samoylenko²,

Reschetnikova³

et al. 2018

PH&LE

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Siberian tick-borne typhus is one of three main tick-borne infections in Russia. The data on the epidemiology of this infection testify not only to varying degrees of epidemic danger of regions, but also on changes in the distribution of risk areas and identify new, epidemiologically significant foci. The criteria for differentiation of focal areas on the risk of infection of the population with the causative agent of Siberian tick-borne typhus have been developed. The ranking is based on the level of morbidity for 1998 - 2016 on 16 endemic territories of the Russia. In accordance with the risk-oriented approach, differentiation of focal areas was carried out with the allocation of epidemiological zones of low, medium, higher than average and high risk of infection. Pronounced heterogeneity of tick-borne rickettsiae circulating in the natural foci noted on molecular biological, antigenic, immunogenic properties and virulence. Data on the main vectors, the transmission mechanism, clinical manifestations, laboratory approaches to diagnosis and preventive therapy. Our findings are important for the organization of epidemiological surveillance of this tick-borne infection.

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Modern Condition of Siberian Tick Typhus Foci

Рудаков¹,

Samoylenko²,

Reschetnikova³

et al. 2018

PH&LE

View full text Add to dashboard Cite

show abstract

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Alteration of Phenotypic Characteristics of Burkholderia Pseudomallei During Interaction With Tetrahymena Pyriformis

Cited by 1 publication

References 7 publications

Modern Condition of Siberian Tick Typhus Foci

Modern Condition of Siberian Tick Typhus Foci

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