Alteration of sarcoplasmic reticulum after denervation of chicken pectoralis muscle

Tate, Charlotte A.; Bick, Roger J.; Myers, Teresa; Pitts, Barry J.R.; Winkle, W. B. Van; Entman, Mark L.

doi:10.1042/bj2100339

Cited by 17 publications

(8 citation statements)

References 34 publications

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“…Previous studies of the SR Ca 2+ regulation following immobilization have shown con¯icting results. Animal models have demonstrated SR Ca 2+ uptake rate to be increased , Patterson & Dettbarn 1985, Stevens & Mounier 1992 or decreased in soleus muscle and in studies of muscle disuse following denervation (Tate et al 1983). Maximal SR Ca 2+ ATPase activity following immobilization has in previous studies been shown not to change , Leivseth et al 1992, or increase markedly (Schulte et al 1993).…”

Section: Discussionmentioning

confidence: 94%

“…Animal models have demonstrated SR Ca 2+ uptake rate to be increased , Patterson & Dettbarn 1985, Stevens & Mounier 1992 or decreased in soleus muscle and in studies of muscle disuse following denervation (Tate et al 1983). Animal models have demonstrated SR Ca 2+ uptake rate to be increased , Patterson & Dettbarn 1985, Stevens & Mounier 1992 or decreased in soleus muscle and in studies of muscle disuse following denervation (Tate et al 1983).…”

Section: Discussionmentioning

confidence: 99%

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Effect of 10‐day cast immobilization on sarcoplasmic reticulum calcium regulation in humans

Thom

Thompson

Ruell

et al. 2001

Acta Physiologica Scandinavica

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This study investigated the effects of 10-day lower limb cast immobilization on sarcoplasmic reticulum (SR) Ca2+ regulation. Muscle biopsies were analysed in eight healthy females for maximal rates of SR Ca2+ release, Ca2+ uptake and Ca2+ ATPase activity at control, during immobilization at day 3 (IM 3), day 6 (IM 6) and day 10 (IM 10). Quadriceps muscle cross-sectional area (CSA) and 1-repetition maximum (1RM) leg extension strength were measured to determine the extent of muscle size and strength adaptations. Muscle CSA and strength decreased following 10 days of immobilization (11.8 and 41.6%, respectively, P < 0.01). A decrease in SR Ca2+ uptake rate (analysed per g wet wt) was found at IM 3 (13.2%, P=0.05), with a further decrease at IM 10 (19.8% from control, P < 0.01). At IM 10, a decrease in SR Ca2+ uptake rate (per mg protein) also occurred (19.9%, P < 0.01). Sarcoplasmic reticulum Ca2+ ATPase activity and rate of Ca2+ release were not altered with 10 days of immobilization. This study observed a decrease in SR Ca2+ uptake rate, muscular atrophy and strength loss over 10 days of immobilization in humans.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Effect of 10‐day cast immobilization on sarcoplasmic reticulum calcium regulation in humans

Thom

Thompson

Ruell

et al. 2001

Acta Physiologica Scandinavica

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“…In mammalian muscles, the more constant Wnding is an increased uptake of Ca 2+ 1-2 weeks after denervation, with a consequent Ca 2+ accumulation in the SR lumen (Brodie 1966;Germinario et al 2002;Margreth et al 1972;Midrio et al 1997;Palexas et al 1982;Salvatori et al 1988;Schulte et al 1994;Sreter 1970;Tate et al 1982;Trachez et al 1990) which can be seen as the consequence of the increase in SR capacity (Midrio et al 1997;Sreter 1970;Zorzato et al 1989) and calsequestrin content of terminal cisternae (Zorzato et al 1989) and/or of a reduced leakage of SR-stored Ca 2+ into myoplasm (Trachez et al 1990;Zorzato et al 1989). The SR Ca 2+ release channels have been reported to be increased in number in rabbit fast muscle, but with a reduced Ca 2+ permeability (Zorzato et al 1989).…”

Section: Changes In Muscle Activation Processmentioning

confidence: 97%

“…The rate of Ca 2+ uptake -reXecting the activity of SR Ca 2+ pumps -has been reported to both increase (Margreth et al 1972;Midrio et al 1997;Trachez et al 1990) and decrease (Palexas et al 1982;Salvatori et al 1988;Schulte et al 1994). In chicken pectoralis muscle, denervation was accompanied by a lower SR Ca 2+ accumulation (Tate et al 1982).…”

Section: Changes In Muscle Activation Processmentioning

confidence: 98%

The denervated muscle: facts and hypotheses. A historical review

2006

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Denervation changes in skeletal muscle (atrophy; alterations of myofibrillar expression, muscle membrane electrical properties, ACh sensitivity and excitation-contraction coupling process; fibrillation), and their possible causes are reviewed. All changes can be counteracted by muscle electrostimulation, while denervation-like effects can be caused by the complete conduction block in muscle nerve. These results do not support the hypothesis that the lack of neurotrophic, non-motor factors plays a role in denervation phenomena. Instead they support the view that the lack of neuromotor discharge is the only cause of the phenomena and that neuromotor activity is an essential factor in regulating muscle properties. However, some experimental results cannot apparently be explained by the lack of neuromotor impulses, and may still suggest that neurotrophic influences exist. A hypothesis is that neurotrophic factors, too feeble to maintain a role in completely differentiated, adult muscles, can concur with neuromotor activity in the differentiation of immature, developing muscles.

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“…These findings suggest that a denervation process of type I1 fibres followed by reinnervation by type I motoneurons underlies, at least in part, the ageing of skeletal muscle. Previous morphological (Pellegrino & Franzini 1963, Muscatello et al 1965) and biochemical (Tate et al 1983, Salvatori et al 1988) studies have shown that denervation of amphibian and mammalian muscles affects the structure of SR, leading to hypertrophy of T C and an increase in the number of triads. We have therefore investigated the effects of ageing on SR of human skeletal muscle.…”

Section: Italymentioning

confidence: 96%

Sarcoplasmic reticulum of human skeletal muscle: age‐related changes and effect of trainirig

Klitgaard

Ausoni

Damiani

1989

Acta Physiologica Scandinavica

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The effect of ageing on human skeletal muscle was investigated using needle biopsies from young and aged subjects and from aged subjects trained with different activity patterns. Histochemical staining for myofibrillar ATPase of ageing m. vastus lateralis demonstrated an unchanged fibre type distribution but a selective atrophy of type IIa and type IIb fibres. Analysis of myosin heavy chain (MHC) composition showed that type I MHC increased with ageing (P less than 0.05). The relative content of the MHC isoforms correlated with the relative area of the respective fibre types. Sarcoplasmic reticulum (SR) proteins were investigated in muscle extracts by electrophoretic and immunoblotting techniques. When compared to a young control group (28 +/- 0.1 years old, n = 7) blots of post-myofibrillar supernatant proteins probed with polyclonal antibodies to the rabbit fast SR Ca-ATPase, a marker of extrajunctional SR, showed that the content of Ca-ATPase was significantly lower (P less than 0.05) in the old control group (68 +/- 0.5 years old, n = 8). On the other hand the content of calsequestrin (CS), the major intraluminal protein of SR terminal cisternae (TC), and of the 350-kDa ryanodine-binding protein, which is localized in the junctional regions of TC, did not show a concomitant decrease. These results suggest that ageing differentially affects extrajunctional and junctional SR of human skeletal muscle. These age-related changes were not observed within a group of old strength-trained subjects.

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Alteration of sarcoplasmic reticulum after denervation of chicken pectoralis muscle

Cited by 17 publications

References 34 publications

Effect of 10‐day cast immobilization on sarcoplasmic reticulum calcium regulation in humans

Effect of 10‐day cast immobilization on sarcoplasmic reticulum calcium regulation in humans

The denervated muscle: facts and hypotheses. A historical review

Sarcoplasmic reticulum of human skeletal muscle: age‐related changes and effect of trainirig

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