Alteration of sonographic texture of the endometrium in post-menopausal bleeding a guide to further management

Sheikh, Mehraj; Sawhney, Sukhpal; Khurana, Ashok; Al‐Yatama, Majda

doi:10.3109/00016340009169250

Cited by 26 publications

(22 citation statements)

References 11 publications

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“…In the present study age range was 41-70 years while in study done by Wong SF et al, Sousa R et al, Bharani B et al, and Sheikh M et al it was 38-94, 43-82, 52-65, 42-84 years respectively. [5,6,7,8] Mean age in the present study was 53.22 years while it was 47.43 to 56.5 years in other studies. 9 It was also observed that as the age of our subjects increased the incidence of postmenopausal bleeding decreased, indicating an inverse relationship between age and age of postmenopausal bleeding.…”

Section: Discussioncontrasting

confidence: 56%

Histopathological Evaluation of Postmenopausal Bleeding

Karmarkar¹,

Wilkinson²,

Rathod³

2014

IOSRJDMS

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Post menopausal bleeding is generally regarded as an ominous and serious alarm of genital pathologies. The term "post menopausal bleeding" generally implies bleeding from the uterus and it is essentially the only bleeding of importance at the postmenopausal age. However in the practical sense the term also includes some instances of bleeding from the vagina, urethra or vulva, in which case a uterine source is held suspect until excluded. Being a symptom of varied etiologies and its strong association with malignancy, it should not be taken lightly. During the present hospital based cross sectional study, we aimed to find out the different histomorphological patterns of the endometrium and cervix, to assess the rate of different benign, premalignant and malignant conditions as a cause of postmenopausal bleeding. 250 specimens were selected. The material for the study was collected from the endometrial curettings, cervical biopsies and hysterectomy specimens sent for histopathological examination. Benign conditions were seen in 206 (82.4%) cases which included atrophic endometrium, proliferative endometrium, secretory endometrium, endometrial polyp, leiomyoma, tuberculous endometritis and simple cystic hyperplasia cases. Premalignant conditions such as hyperplasia with atypia were seen in 18 (7.2%) cases. Endometrial adenocarcinoma, cervical squamous cell carcinoma and Mixed Mullerian tumor [MMT] were the malignant condition seen in 26 (10.4%) cases.

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Section: Discussioncontrasting

confidence: 56%

Histopathological Evaluation of Postmenopausal Bleeding

Karmarkar¹,

Wilkinson²,

Rathod³

2014

IOSRJDMS

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“…Especially in patients with a suspected diagnosis of submucosal fibroids or endometrial polyps, the success of hysteroscopy on the diagnosis has been shown to be between 53-97%. 20,21 Hysteroscopic myomectomy should be considered firstline conservative surgical therapy for the management of symptomatic submucosal myomas. 22 It is highly effective in resolving abnormal bleeding, with a success rate between 70-90%.…”

Section: Discussionmentioning

confidence: 99%

The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness

Seçkin

Karslı

Yücel

et al. 2016

Gynecol Obstet Reprod Med

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OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding. STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups. RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p>0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p<0,05). CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure.

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“…There are, however, several studies showing that endometrial morphology assessment can be useful in the prediction of endometrial cancer 20 – 23 . Endometrial echogenicity and border in combination with ET has been shown to be a better predictor of endometrial cancer than ET measurement alone 21 – 23 . The best predictor of cancer at SIS is the finding of an irregular surface focal lesion (sensitivity 89% specificity 67%), Fig.…”

Section: Novel Techniques For Risk‐estimation Of Endometrial Malignanmentioning

confidence: 99%

The use of new and old ultrasound techniques in the assessment of women with postmenopausal bleeding

Epstein

2009

Australas J Ultrason Med

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Alteration of sonographic texture of the endometrium in post-menopausal bleeding a guide to further management

Cited by 26 publications

References 11 publications

Histopathological Evaluation of Postmenopausal Bleeding

Histopathological Evaluation of Postmenopausal Bleeding

The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness

The use of new and old ultrasound techniques in the assessment of women with postmenopausal bleeding

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