Alterations in “in vivo” histology of retina in bilateral chronic central serous chorioretinopathy after intravitreal bevacizumab

Saxena, Sandeep; Jain, Astha

doi:10.1007/s12177-012-9077-y

Cited by 1 publication

(1 citation statement)

References 19 publications

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“… 84 Previous study has shown that the transverse length of the disrupted or absent ISel band has been related to visual impairment. 85 Our recent study demonstrated that increased levels of serum vascular endothelial growth factor and intercellular adhesion molecule-1 levels in diabetic retinopathy are associated with an increase in the severity of diabetic retinopathy and the grade of subfoveal ELM and ISel band disruption. Disruption of the photoreceptor ISel band and ELM was graded by SD-OCT as follows: grade 0 being no disruption of ELM and ISel band ( Figure 8A ), grade 1 being ELM disrupted with intact ISel band ( Figure 8B ), and grade 2 having both ELM and ISel band disrupted ( Figure 8C ).…”

Section: Inner Segment Ellipsoid In Medical Retinal Diseasesmentioning

confidence: 94%

Photoreceptor inner segment ellipsoid band integrity on spectral domain optical coherence tomography

Saxena¹,

Srivastav²,

Cheung³

et al. 2014

OPTH

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Spectral domain optical coherence tomography cross-sectional imaging of the macula has conventionally been resolved into four bands. However, some doubts were raised regarding authentication of the existence of these bands. Recently, a number of studies have suggested that the second band appeared to originate from the inner segment ellipsoids of the foveal cone photoreceptors, and therefore the previously called inner segment-outer segment junction is now referred to as inner segment ellipsoidband. Photoreceptor dysfunction may be a significant predictor of visual acuity in a spectrum of surgical and medical retinal diseases. This review aims to provide an overview and summarizes the role of the photoreceptor inner segment ellipsoid band in the management and prognostication of various vitreoretinal diseases.

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Section: Inner Segment Ellipsoid In Medical Retinal Diseasesmentioning

confidence: 94%