Alterations of pancreatic functions and lipid profiles in dairy cows with left displacement of the abomasum

Abstract

The objectives of this study were to determine the serum activities of the pancreatic enzymes amylase, lipase, trypsinogen 1 and trypsinogen 2, serum concentrations of total cholesterol, high density lipoprotein, low-density lipoprotein and triglycerides and serum inflammatory indicators, namely C-reactive protein and procalcitonin, in Holstein-Friesian dairy cows with left displacement of the abomasum (LDA). A total of 60 cows (30 LDA-affected and 30 healthy) were included in the study. Laboratory analyses were performed using commercially available ELISA kits and chemical reagents according to the manufacturers’ recommendations. There was a significant increase (P ≤ 0.05) in the activities of lipase, trypsinogen 1 and trypsinogen 2 in LDA-affected cows compared to healthy cows. Amylase concentrations, however, remained unchanged. The serum concentrations of total cholesterol and high-density lipoprotein were significantly (P ≤ 0.05) increased in LDA-affected cows while the concentrations of low-density lipoprotein and triglycerides were significantly (P ≤ 0.05) decreased compared to healthy cows. Procalcitonin and C-reactive protein concentrations were significantly (P ≤ 0.05) increased in LDA-affected cows compared to healthy cows. This study indicates that displacement of the abomasum may be associated with significant pathological effects in the pancreas that may affect cows in the post-operative period.

Biomarkers of sepsis in pigs, horses and cattle: from acute phase proteins to procalcitonin

“…In pigs, only a few studies with induced experimental infections found measurable concentrations of plasmatic PCT, maybe due to the lack of specificity of the methods (Wagner et al ., 2002; Zannoni et al ., 2012; Spyropoulos et al ., 2019; Liu et al ., 2021). To the authors’ knowledge, very few studies have evaluated PCT in non-septic inflammation (Ismail et al ., 2019; Kilcoyne et al ., 2020), and there are no studies about the role of PCT during viral pathologies in animals.…”

Ultrasonography of left displaced abomasum in local cattle breed

“…Heavy losses in dairy farm can occur because left displaced abomasum (LDA) can cause decrease in daily milk especially around highly production period 3 months after calving (1). Many predisposing factors can take part in the occurrence of LDA as hypocalcaemia, ketosis, Fatty liver, dystocia and inflammatory processes (2,3). Development of LDA depends on three factors: abomasal atony, rumen size and postpartum abdominal gap (4).…”