2023
DOI: 10.3389/fneur.2023.1297028
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Altered cortical and subcortical morphometric features and asymmetries in the subjective cognitive decline and mild cognitive impairment

Jin Yang,
Lingyan Liang,
Yichen Wei
et al.

Abstract: IntroductionThis study aimed to evaluate morphological changes in cortical and subcortical regions and their asymmetrical differences in individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). These morphological changes may provide valuable insights into the early diagnosis and treatment of Alzheimer's disease (AD).MethodsWe conducted structural MRI scans on a cohort comprising 62 SCD patients, 97 MCI patients, and 70 age-, sex-, and years of education-matched healthy controls… Show more

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