Altered Emotional Perception in Alcoholics: Deficits in Affective Prosody Comprehension

Monnot, Marilee; Nixon, Sara Jo; Lovallo, William R.; Ross, Elliott M.

doi:10.1097/00000374-200103000-00007

Cited by 38 publications

(47 citation statements)

References 27 publications

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“…Most studies aiming at identifying the sources of social difficulties in AD individuals have focused on difficulties in emotional processing. For example, it has been shown that AD individuals have difficulties recognizing emotion expressions (especially anger) from faces (Kornreich et al, 2003;Maurage et al, 2011), postures (Maurage et al, 2009), or voice prosody (Monnot et al, 2001).…”

mentioning

confidence: 99%

Theory of Mind Difficulties in Patients with Alcohol Dependence: Beyond the Prefrontal Cortex Dysfunction Hypothesis

Maurage

Timary

Tecco

et al. 2015

Alcoholism Clin & Exp Res

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mentioning

confidence: 99%

Theory of Mind Difficulties in Patients with Alcohol Dependence: Beyond the Prefrontal Cortex Dysfunction Hypothesis

Maurage

Timary

Tecco

et al. 2015

Alcoholism Clin & Exp Res

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“…Researchers have noted overlaps between the pragmatic impairments associated with RHD and those seen in people with autistic spectrum disorders (Ellis & Gunter, 1999;Ozonoff & Miller, 1996), schizophrenia (Mitchell & Crow, 2005), semantic-pragmatic disorder (Shields, 1991), traumatic brain injury (Martin & McDonald, 2003 (Cherney & Canter, 1993), alcoholism (Monnot, Nixon, Lovallo, & Ross, 2001), as well as in healthy elderly people (Kjelgaard, Titone, & Wingfield, 1999).…”

Section: Pragmatics Rhd and Other Clinical Groupsmentioning

confidence: 99%

What's left to learn about right hemisphere damage and pragmatic impairment?

Weed

2011

Aphasiology

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Background:The nature and causes of pragmatic impairments following right hemisphere damage (RHD) continue to pose a challenge to researchers and clinicians. It is widely accepted that impairment in pragmatic and para-linguistic aspects of language can result from unilateral damage to the right hemisphere (RH), but it still uncertain exactly what the RH's special contributions to these areas of language and communication is. Advancing our understanding of the RH's role in pragmatics and communication will require a theoretical framework for pragmatics that is suited to the clinical environment. Aims: I first sketch several theoretical approaches to pragmatics, and suggest that Perkins' (2007) emergentist approach to pragmatics is the best suited to describing and explaining communication difficulties in a clinical setting. I then consider some of the implications of adopting the emergentist approach for research on pragmatic impairment in RHD by describing three relatively unexplored areas of research in the domain of RHD and pragmatics: application of conversation analysis techniques, investigation of the contribution of perceptual impairments to pragmatic impairment, and the comparison of pragmatic impairment across clinical groups. Main Contribution: I propose that the emergentist approach to pragmatics provides a useful framework for investigating issues of pragmatic impairment in RHD and other clinical groups, and show how adopting this approach naturally leads to research in three relatively unexplored areas. Conclusions: I argue that pursuing these lines of investigation will help move forward research in RHD, pragmatic impairment, and the general role of the right hemisphere in pragmatics.

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“…19,20 The Aprosodia Battery (ApB) has been used as an effective research tool in various clinical populations. 21,[36][37][38][39] For details concerning the rational, administration, acoustic measurements and scoring of the ApB see reference 15 and the Appendix. Affective-prosodic production includes tasks of Spontaneous production and Repetition involving Word, Monosyllabic, and Asyllabic stimuli.…”

Section: Testing Proceduresmentioning

confidence: 99%

Relationship of Leukoaraiosis to Cognitive Decline and Cognitive Aging

Ross¹,

Hansel²,

Orbelo³

et al. 2005

Cognitive and Behavioral Neurology

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Objective: Leukoaraiosis (LA) is a common finding on MRI scans of the elderly. However, its exact relationship to cognitive decline and dementia is in dispute. Because LA involves the paracallosal white matter, we sought to determine if LA, uncomplicated by ischemic lesions or complaints of cognitive impairment, is associated with cognitive loss or difficulties with interhemispheric integration of behavioral functions.Methods: Two hundred fifty-seven MRI scans with deep white matter changes were screened. After a chart review, 38 patients had uncomplicated LA, and 31 gave informed consent to undergo cognitive and behavioral testing.Results: LA severity was not related to any of the cognitive or behavioral assessments. However, some dependent measures showed medium effect sizes that were in keeping with published findings, indicating that LA has a marginal impact on cognition. In comparison, robust relationships with age were found for certain tasks, suggesting that our cohort size was sufficient to detect meaningful clinical relationships.Conclusion: Based on statistical interpretations using effect sizes, LA severity may be better viewed as a biomarker for physiological brain aging that is in advance of chronological age, leaving the elderly individual at greater risk for developing dementia.A lthough leukoaraiosis (LA) is a common finding on MRI scans, its pathophysiologic significance is not fully understood ( Fig. 1). 1-6 LA is most strongly associated with being elderly. Hypertension, diabetes mellitus, coronary artery disease, smoking, and noncoronary arterial vascular disease are additional risk factors. However, its relationship to normal cognitive aging and dementia is not yet known. 6 Some investigators have suggested that its presence may speed the dementia process. Others have hypothesized that LA is a possible risk factor for both dementia and lacunar stokes. 7 Yet, a study using both functional and static imaging techniques found no relationships between LA severity or presence of lacunar infarcts and either cognitive deficits, brain atrophy, or changes in regional cerebral blood flow or glucose metabolism, whereas changes in regional cerebral blood flow and glucose metabolism appropriately predicted cognitive deficits and brain atrophy. 3 Some studies have been able to show weak associations of LA severity to gait disturbances and selected neuropsychologic assessments, such as the Wisconsin Card Sort Test (WCST), Trail Making Test B, Digit Span Forward, and Mini-Mental State Examination (MMSE), whereas others have not. [8][9][10][11][12][13][14][15][16][17] In a recent meta-analysis of the relationship between LA and cognitive impairment, Gunning-Dixon and Raz 18 found that LA is associated with poorer performance on tasks requiring executive functions, processing speed, delayed memory, and global indices of cognitive functions but not indices involving ''psychometric intelligence.'' However, when reviewing the effect sizes for the significant associations using r 2 values calculated from the pap...

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Altered Emotional Perception in Alcoholics: Deficits in Affective Prosody Comprehension

Cited by 38 publications

References 27 publications

Theory of Mind Difficulties in Patients with Alcohol Dependence: Beyond the Prefrontal Cortex Dysfunction Hypothesis

Theory of Mind Difficulties in Patients with Alcohol Dependence: Beyond the Prefrontal Cortex Dysfunction Hypothesis

What's left to learn about right hemisphere damage and pragmatic impairment?

Relationship of Leukoaraiosis to Cognitive Decline and Cognitive Aging

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