“…One of the biggest genome-wide association studies (GWASs) on VVs was performed by the American 23andMe company scientists who identified a group of 12 SNPs and genes corresponding to them: rs507666 (ABO), rs966562 (XKR5, ANGPT2, AGPAT5), rs7111987 (ADM, AMPD3), rs11121615 (CASZ1), rs111434909 (ANGPT1), rs145218303 (ARGHAP6), rs6905288 (VEGFA), rs4516218 (PIEZO1), rs4463578 ( ZIC3, FGF13), rs6062618 (SOX18, TCEA2), rs6712038 (PPP3R1, CNRIP1) and rs79607156 (THEG5, ZNF507) [21] . However, those associations were not replicated.…”