Altered Hemodynamics in the Pulmonary Circulation Following Reaeration of an Atelectatic Lung

Long, Esmond R.; Adams, William E.; Benfield, John R.; Mikouchi, Takemaru; Reimann, Arthur F.; Nigro, S. Ló

doi:10.1016/s0022-5223(19)32587-5

Cited by 13 publications

(6 citation statements)

References 11 publications

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“…Restricted oxygen penetration to the alveoli results in a decreased flow of only 7 -15 % of cardiac output through the atelectatic lung [2,3]. Ventilation is diminished to 24 %, and oxygen uptake to 14 % of the respective predicted values [4]. In animal experiments, Ahmed et al found that vessel intima and the muscular layer became thicker, leading to a permanent narrowing of the arteries; however this was not confirmed by other authors [1,2].…”

Section: Discussionmentioning

confidence: 99%

“…Lung expansion leads to a restoration of gas exchange and perfusion [3] but pulmonary artery pressure remains elevated. In their experimental studies on hemodynamics in the pulmonary circulation in dogs, Benfield et al confirmed restoration of lung function following re-aeration of an atelectatic lung but observed that the same animals did not survive contra-lateral pneumonectomy a few weeks later [3,4]. The dogs died with an oedematous condition in the remaining re-aerated lung, with dilatation of the right ventricle and congestion of the liver.…”

Section: Introductionmentioning

confidence: 98%

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Lung Function in Patients Operated for Chronic Pleural Empyema

Rzyman

Skokowski²,

Romanowicz³

et al. 2005

Thorac cardiovasc Surg

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Lung Function in Patients Operated for Chronic Pleural Empyema

Rzyman

Skokowski²,

Romanowicz³

et al. 2005

Thorac cardiovasc Surg

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“…[4,5] Some studies have also reported that reduced ventilation, perfusion, and oxygen uptake in atelectatic lungs improved after the lung was re-expanded. [6][7][8] The aim of this study was to evaluate pulmonary function before and after surgery in patients who underwent lung decortication due to pleural empyema and to compare the results obtained with those in the literature.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Pleural Decortication on Respiratory Functions of The Patients Having Pleural Empyemas

Özer¹

2018

South Clin Ist Euras

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Objective: Pleural empyema is a collection of purulent liquid in the cavity between the visceral and parietal pleura developing during the postinflammatory period. It can have a high morbidity and mortality rate if not treated. The aim of this study was to spirometrically evaluate respiratory function in patients before and after decortication surgery, which is a treatment used in late phase, chronic pleural empyema. Methods: Patient files were evaluated retrospectively according to the criteria of the study. Forced expiratory volume-1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC% values measured in the week before surgery and 6 months after the procedure were then compared with preoperative values. Results: A significant improvement was seen in spirometric values. The mean preoperative values of FVC 2.33±0.71 L, FEV1 1.91±0.56 L, and FEV1/FVC% 82.77±8.50% increased postoperatively to 2.64±0.65 L (p=0.000), 2.28±0.57 L (p=0.000), and 86.52±7.47% (p=0.014), respectively. The increase in postoperative values for FVC, FEV1, and FEV1/FVC% were 13.3%, 19.3%, and 4.53%, respectively. These results were statistically quite significant for FVC, FEV1, and significant for FEV1/FVC. Conclusion: The results indicate that decortication is an effective operation to treat eligible stage III empyema patients.

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“…[8][9][10] Some authors reported significant reduction of perfusion, ventilation and oxygen uptake in the atelectatic lung, which resolved significantly after reexpansion. 4,11,12 It has also been reported that pulmonary function did not improve or even deteriorated after the decortication when the cause for the primary disease was tuberculosis. 8,9,13 The aim of this study was to add further information about lung functions before and after lung decortication in young adults with tuberculosis/non-tuberculosis causes.…”

Section: Introductionmentioning

confidence: 99%

“…Although many authors have reported no or minimal improvement in lung functions, decortication is usually followed by an improvement in spirometric parameters, such as vital capacity (VC), total capacity and maximal breathing capacity 8–10 . Some authors reported significant reduction of perfusion, ventilation and oxygen uptake in the atelectatic lung, which resolved significantly after re‐expansion 4,11,12 . It has also been reported that pulmonary function did not improve or even deteriorated after the decortication when the cause for the primary disease was tuberculosis 8,9,13 .…”

Section: Introductionmentioning

confidence: 99%