Altered Lymphatic Drainage After Breast-Conserving Surgery and Axillary Node Dissection: Local Recurrence with Contralateral Intramammary Nodal Metastases

Wellner, Rachel; Dave, Jasmine; Kim, Unsup; Menes, Tehillah S.

doi:10.3816/cbc.2007.n.006

Cited by 27 publications

(16 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Metastasis to the contralateral axilla is classically termed metastatic disease in the absence of disease in the contralateral breast. However, aberrant lymphatic spread may occasionally occur especially after occlusion of conventional pathways of lymphatic drainage following axillary dissection or irradiation [5,6]. A lymphoscintigraphy study on 23 patients of operable breast cancer before and after therapy that included axillary dissection, irradiation, or both, determined that the incidence of contralateral axillary lymph node spread increased from 1/23 at baseline to 6/23 after therapy [7].…”

Section: Discussionmentioning

confidence: 99%

Breast cancer with inguinal node recurrence

Goyal

Puri

Julka

2015

Journal of the Egyptian National Cancer Institute

View full text Add to dashboard Cite

Surgery and irradiation for breast cancer may interfere with conventional pathways of spread, leading to bizarre patterns of dissemination through lymphatics or through hematogenous route. Lymphoscintigraphic studies may help identify nodal involvement. Other possible reasons could be occurrence of primary breast cancer in accessory breast tissue retained in the vulva following involution of milk line. We describe a case of triple negative breast cancer, who developed contralateral breast cancer during treatment. Three years later, she developed isolated inguinal nodal metastases, which responded to local radiotherapy and chemotherapy. However, the patient relapsed after 2 years and could not be salvaged thereafter.

show abstract

Section: Discussionmentioning

confidence: 99%

Breast cancer with inguinal node recurrence

Goyal

Puri

Julka

2015

Journal of the Egyptian National Cancer Institute

View full text Add to dashboard Cite

show abstract

“…Changes in axillary and internal mammary lymph node drainage were noted in 68% of patients . Reports of lymphatic drainage to the contralateral internal mammary system highlights the need to be prepared for the unexpected in a setting of revision surgery …”

Section: Discussionmentioning

confidence: 99%

“…8 Reports of lymphatic drainage to the contralateral internal mammary system highlights the need to be prepared for the unexpected in a setting of revision surgery. 9 An alternative hypothesis is the seeding of malignant cells in the central neck at the time of prior tracheotomy. Although this has been reported, it would be expected to recur as soft tissue deposit, rather than within lymph nodes.…”

Section: Discussionmentioning

confidence: 99%

Oral cavity squamous cell carcinoma metastatic to central compartment (level 6) lymph nodes

et al. 2015

View full text Add to dashboard Cite

Alterations to drainage pathways in the head and neck as a result of surgical manipulation are not well understood. We present two unusual cases of oral squamous cell carcinoma metastatic to the level 6 nodal compartment following extensive treatment. Both oral squamous cell carcinoma cases exhibited metastases to the central neck compartment following extensive surgery and radiation. Each patient had prior history of multifocal oral cavity disease and recurrent neck metastases requiring salvage lymphadenectomy. Surgical interventions may alter the usual lymphatic drainage patterns. In cases of extensive treatment, all levels of the neck should be monitored for lymph node recurrence. Laryngoscope, 126:1803-1805, 2016.

show abstract

“…One patient with a CLNR in the internal mammary chain was described. 9 In a total of 19 patients (39.6%) the method of excluding a contralateral breast tumour was recorded. This varied between prophylactic contralateral mastectomy (N ¼ 2), to several radiological examinations; breast imaging was not specified in one patient, for other patients mammography only (N ¼ 5), mammography and MRI (N ¼ 3), MRI only (N ¼ 3), MRI and PET-CT (N ¼ 3) or PET-CT only (N ¼ 2) were performed.…”

Section: Detection Methodsmentioning

confidence: 99%