2023
DOI: 10.1101/2023.12.04.569509
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Altered Orbitofrontal Cortex Activation and Gaze Patterns to Happy Faces in Autistic Children Predict Adaptive Difficulties but Challenge the Social Motivation Hypothesis

Mengyuan Yang,
Lan Zhang,
Zijie Wei
et al.

Abstract: Individuals diagnosed with Autism Spectrum Disorder (ASD) generally have altered responses to social reward, which the “social motivation” hypothesis posits as the primary contributor to their social deficits. Aberrant perception of rewarding faces is considered to be one of the most significant markers of this hypothesis. The orbitofrontal cortex (OFC) plays an important role in modulating reward and arousal responses to happy faces but few studies have investigated whether young autistic children with limite… Show more

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