Comprehensive Physiology 1977
DOI: 10.1002/cphy.cp090141
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Altered Protein Synthesis

Abstract: The sections in this article are: Inhibition of Protein Synthesis Puromycin Ethionine Sparsomycin Hypertonicity of Portal Blood Enhancement of Protein Synthesis Alterations or Imbalances in Nutrition Hormones, Toxins, Physical Agen… Show more

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“…Although the inhibitory effects were similar under the two different experimental conditions, the mechanism for each may be different in that the NaCl concentration in hepatic cells after administration of NaCl in vivo was appreciably higher than the low levels added in vitro to the isolated hepatic nuclei. added sodium chloride; nuclear envelopes; rats THE ENHANCEMENT OF HEPATIC protein synthesis in mice, rats, rabbits, and pigs, which is rapidly induced by the administration of L-tryptophan (27,(29)(30)(31)(32)(33)35), has been the central focus of our interest for many years. In attempting to unravel the mechanism involved in this stimulatory response, we have discovered that hepatic nuclei, particularly their nuclear envelopes, have a specific receptor for L-tryptophan (15,16).…”
mentioning
confidence: 99%
“…Although the inhibitory effects were similar under the two different experimental conditions, the mechanism for each may be different in that the NaCl concentration in hepatic cells after administration of NaCl in vivo was appreciably higher than the low levels added in vitro to the isolated hepatic nuclei. added sodium chloride; nuclear envelopes; rats THE ENHANCEMENT OF HEPATIC protein synthesis in mice, rats, rabbits, and pigs, which is rapidly induced by the administration of L-tryptophan (27,(29)(30)(31)(32)(33)35), has been the central focus of our interest for many years. In attempting to unravel the mechanism involved in this stimulatory response, we have discovered that hepatic nuclei, particularly their nuclear envelopes, have a specific receptor for L-tryptophan (15,16).…”
mentioning
confidence: 99%