2023
DOI: 10.1017/s003329172300168x
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Altered topology of individual brain structural covariance networks in major depressive disorder

Abstract: Background The neurobiological pathogenesis of major depression disorder (MDD) remains largely controversial. Previous literatures with limited sample size utilizing group-level structural covariance networks (SCN) commonly generated mixed findings regarding the topology of brain networks. Methods We analyzed T1 images from a high-powered multisite sample including 1173 patients with MDD and 1019 healthy controls (HCs). We used regional gray matter volume to construct individual SCN by u… Show more

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References 70 publications
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