2023
DOI: 10.1177/10870547231167499
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Altered White Matter Integrity in ADHD Revealed by Meta-analysis of Tract-based Spatial Statistics

Abstract: Objective: We conducted an updated coordinate-based meta-analysis (CBMA) to determine the most prominent and robust white matter (WM) abnormalities in ADHD based on tract-based spatial statistics (TBSS) findings. Method: The seed-based d mapping (SDM) software was applied to compare regional fractional anisotropy (FA) alterations in ADHD. Subgroup meta-analyses in the pure ADHD without comorbidity subgroup, the children and adolescents subgroup, and the adults subgroup were also explored, respectively. Meta-re… Show more

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Cited by 2 publications
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“…CBMA helps to address inconsistencies in results across different studies, thereby enhancing understanding of speci c structures or functions in the nervous system. In the eld of mental health, CBMA has been applied to investigate changes in brain cortical structure such as major depressive disorder (MDD) (Zhang et al, 2023), post-traumatic stress disorder (PTSD)(L. , attention de cit hyperactivity disorder (ADHD) (Cui et al, 2023), autism spectrum disorder (ASD) (Shen et al, 2024), and other neurological disorders such as Parkinson disease(PD)(L et al, 2020). By integrating results from multiple studies, CBMA can reveal common patterns of change in the brain associated with these disorders, facilitating a deeper understanding of the neurobiological mechanisms underlying these conditions.…”
Section: Introductionmentioning
confidence: 99%
“…CBMA helps to address inconsistencies in results across different studies, thereby enhancing understanding of speci c structures or functions in the nervous system. In the eld of mental health, CBMA has been applied to investigate changes in brain cortical structure such as major depressive disorder (MDD) (Zhang et al, 2023), post-traumatic stress disorder (PTSD)(L. , attention de cit hyperactivity disorder (ADHD) (Cui et al, 2023), autism spectrum disorder (ASD) (Shen et al, 2024), and other neurological disorders such as Parkinson disease(PD)(L et al, 2020). By integrating results from multiple studies, CBMA can reveal common patterns of change in the brain associated with these disorders, facilitating a deeper understanding of the neurobiological mechanisms underlying these conditions.…”
Section: Introductionmentioning
confidence: 99%