After an explosion, determining the remaining capacity of a structure to resist a progressive collapse can provide valuable information for emergency operations and decision makers. Condition assessments after a blast are commonly performed with a visual inspection. However, visual inspections can be time-consuming and involve putting additional personnel into harm’s way. Analytical blast analyses can estimate a structures post-blast condition, but to achieve a high level of accuracy these analyses can be time-consuming and require information regarding the blast event which may not be available at the time. This presents a need for a threat independent post-blast analysis method, which can assess for the post-blast structural condition without requiring personnel to enter the structure. The alternate path method has been used to design buildings to resist a progressive collapse; however, it does not incorporate damage outside of element failure making it unsuitable for post-blast condition assessments. Model updating using modal properties from vibration measurements has been used in structural health monitoring to estimate damage on structures, but it has not been applied to post-blast structures. In this article, a method to estimate the remaining elemental structural capacity of a post-blast structure, called the adaptive alternate path analysis, is presented. This method involves using the alternate path method to assess an updated numerical model, which incorporates the buildings’ structural damage. To demonstrate the impact of incorporating additional damage beyond elemental failure on a structure’s capacity, a simulated study is presented using simulated stiffness reductions. A blast simulation is then used to show the capacity of the updated numerical model to represent the post-blast structure and the improvements gained over using the original model. The presented methodology can be used to assess a structures potential for progressive collapse after a blast, leading to safer emergency operations.