Alternate release of different target species based on the same gold nanorods and monitored by cell imaging

Chen, Shenna; Huang, Haowen; Zhang, Lingyang; Chen, Yun; Liu, Xuanyong

doi:10.1016/j.colsurfb.2016.05.087

Cited by 3 publications

(1 citation statement)

References 52 publications

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“…These can produce nanorod samples with a wide range of tunable, longitudinal surface plasmon resonances (LSPRs), which correlate with their aspect ratios (Schmucker et al 2010, Hu et al 2014a, 2014b. Optical applications of gold nanorods include sensing and imaging based on light absorption (Murphy et al 2005), laser-induced heating (Perez-Juste et al 2005), photothermal cancer therapy (Huang et al 2007, Wang et al 2011, Alkilany et al 2012, Zhang et al 2012, Dembereldorj et al 2014, surface plasmon resonance-enhanced properties plus Raman scattering (Huang et al 2007), plasmon-induced charge separation (Du et al 2009, Kou et al 2016, drug delivery (Alkilany et al 2012, Chen et al 2016, and sensing the deformational mechanics fields of living cells (Murphy et al 2008), to name a few. Biological applications of gold nanorods are expected to increase due to their excellent biocompatibility (Huang et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Differentiating gold nanorod samples using particle size and shape distributions from transmission electron microscope images

Grulke

et al. 2018

Metrologia

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Size and shape distributions of gold nanorod samples are critical to their physico-chemical properties, especially their longitudinal surface plasmon resonance. This interlaboratory comparison study developed methods for measuring and evaluating size and shape distributions for gold nanorod samples using transmission electron microscopy (TEM) images. The objective was to determine whether two different samples, which had different performance attributes in their application, were different with respect to their size and/or shape descriptor distributions. Touching particles in the captured images were identified using a ruggedness shape descriptor. Nanorods could be distinguished from nanocubes using an elongational shape descriptor. A nonparametric statistical test showed that cumulative distributions of an elongational shape descriptor, that is, the aspect ratio, were statistically different between the two samples for all laboratories. While the scale parameters of size and shape distributions were similar for both samples, the width parameters of size and shape distributions were statistically different. This protocol fulfills an important need for a standardized approach to measure gold nanorod size and shape distributions for applications in which quantitative measurements and comparisons are important. Furthermore, the validated protocol workflow can be automated, thus providing consistent and rapid

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Section: Introductionmentioning

confidence: 99%

Differentiating gold nanorod samples using particle size and shape distributions from transmission electron microscope images

Grulke

et al. 2018

Metrologia

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Prompting peroxidase-like activity of gold nanorod composites by localized surface plasmon resonance for fast colorimetric detection of prostate specific antigen

Tan

Yang

Xie

et al. 2018

Analyst

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The interaction between incident light and surface electrons in conductive nanoparticles produces localized plasmon oscillations with a resonant frequency that strongly depends on the composition, size, geometry, and dielectric environment. Hybrid heterostructure materials combining two or more materials in one structure represent a powerful way to achieve unique properties and multifunctionality compared to those of the individual nanoparticle components. Hybrid gold nanorods and gold nanoclusters (GNR/AuNCs) heterostructures prepared by intimate integration of GNRs with AuNCs exhibit both localized surface plasmon resonance (LSPR) property and peroxidase-like activity. It is found that the catalytic activity of the AuNC/GNR heterostructure could be remarkably enhanced by LSPR induced by photon-plasmon coupling in the visible to near-infrared (NIR) region. Meanwhile, the catalytic activity of enzyme-like AuNC/GNRs may be regulated by immunoreactions to realize specific recognition of a target analyte. Accordingly, a fast colorimetric assay within 5 min for the detection of prostate specific antigen (PSA) was developed based on a AuNC/GNRs heterostructure mask regulated by the target molecule under photon-plasmon coupling. The color intensity is inversely proportional to the PSA concentration, and quantitative analysis may be achieved in a range of 10 and 200 pg mL-1. This sensor was practically applied to detect PSA levels in prostate cancer serum samples and the determined values agreed well with those measured by the hospital using standard methods. This indicates that the AuNC/GNRs heterostructure-based assay has high accuracy for the analysis of practical samples. Moreover, the new method has the advantages of very fast determination and low sample volume requirements.

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Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers - A Review

Mbugua

Njenga

Odhiambo

et al. 2021

CTMC

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: Modern anticancer drugs target DNA specifically on rapid division of malignant cells. One downside of this approach is that they also target other rapidly dividing healthy cells such as those involved in hair growth leading to serious toxic side effects and hair loss. Therefore, it would be better to develop novel agents that address cellular signalling mechanisms unique to cancerous cells, and new research is now focussing on such approaches. Although the classical chemotherapy area involving DNA as the set target continues to produce important findings, nevertheless, a distinctly discernible emerging trend is the divergence from the cisplatin operation model that uses the metal as the primary active centre of the drug. Many successful anti-cancer drugs present are associated with elevated toxicity levels. Cancers also develop immunity against most therapies and the area of cancer research can therefore be seen as an area with a high unaddressed need. Hence, ongoing work into cancer pathogenesis is important to create accurate preclinical tests which can contribute to the development of innovative drugs to manage and treat cancer. Some of the emergent frontiers utilizing different approaches include nanoparticles delivery, use of quantum dots, metal complexes, tumour ablation, magnetic hypothermia and hyperthermia by use of Superparamagnetic Iron oxide Nanostructures, pathomics and radiomics, laser surgery and exosomes. This review summarizes these new approaches in good detail giving critical views with necessary comparisons. It also delves into what they carry for the future including their advantages and disadvantages.

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Alternate release of different target species based on the same gold nanorods and monitored by cell imaging

Cited by 3 publications

References 52 publications

Differentiating gold nanorod samples using particle size and shape distributions from transmission electron microscope images

Differentiating gold nanorod samples using particle size and shape distributions from transmission electron microscope images

Prompting peroxidase-like activity of gold nanorod composites by localized surface plasmon resonance for fast colorimetric detection of prostate specific antigen

Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers - A Review

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