spine with angle between the horizontal plane and the lead between 0° and 60°. 7 The other is the characteristic ECG pattern (ie, especially negative QRS complexes in lead I; the presence of q wave in lead I). All studies (randomized or nonrandomized), which studied RV apical versus RV nonapical pacing, have used one of these criteria for assessment of the correct location of the lead in the septal part of the RV. However, the interventricular septum is not visible on fluoroscopy. The rotation of the heart and various shapes of the RV makes it difficult to assess the correct anchor point for the RV lead. Therefore, targeting the midseptum may be technically challenging because it is based mainly on fluoroscopy and the question remains, even if it fulfills fluoroscopic or ECG criteria, whether the lead is really anchored in the septum. Very recently, some reports have been published, which questioned the LAO criterion. Original ArticleBackground-The aim of the study was to verify the correct anchoring location for the tip of the right ventricular lead using cardiac computed tomography and to assess the best fluoroscopic and ECG criteria associated with the correct location of the electrode into the midseptum. Methods and Results-Patients indicated to pacemaker implantation were prospectively enrolled. The right ventricular lead was implanted into the midseptum according to standard criteria in left anterior oblique 40 view. The cardiac shadow on the right anterior oblique 30 was divided into 4 quadrants perpendicular to the lateral cardiac silhouette and the position of the lead tip was analyzed. The exact position of the lead tip was assessed using computed tomography. Of 51 patients, the right ventricular lead was anchored midseptum in 21 (41.2%; MS group). In 30 patients (58.8%; non-MS group), the lead was anchored in the adjacent anterior wall. The angle between the lead and horizontal axis on the left anterior oblique was similar in both groups. The non-MS group was associated with shorter distances between the tip and the cardiac contours in the right anterior oblique 30 (96.7% of leads in the non-MS group were in the outer quadrant versus 9.6% in the MS group; P<0.001). The presence of the lead in the middle or inferior quadrants was independently associated with correct midseptum placement with positive predictive value of 94.7%.
Conclusions-Despite