Hip resurfacing arthroplasty has been a popular alternative for total hip replacement in young active patients since the early 1990s.Early results have been promising and a large number of arthroplasties were performed in the United Kingdom, North America, and Western Europe during the last decade. However, due to a series of complications, such as pseudo-tumours, femoral neck fractures avascular necrosis and aseptic loosening, the long-term results were poor and failure rate has been high. This chapter attempts to identify the different biological and biomechanical mechanisms that may contribute to these failures. It also discusses some considerations to be noted when designing resurfacing implants in the future. This is a research study based on the author's primary research work carried out with retrieval specimens taken from failed hip arthroplasties.